Protein Alignment Alp8 and Akp3

DIOPT Version :10

• Sequence 1: NP_611655.1
• Gene: Alp8 / 37540
• FlyBaseID: FBgn0034712
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_073171.2
• Gene: Akp3 / 64621
• RGDID: 621650
• Length: 558
• Species: Rattus norvegicus
• Alignment Length: 496
• Identity: 204/496 - (41%)
• Similarity: 281/496 - (56%)
• Gaps: 35/496 - (7%)

  Fly    42 KLKFSTDVATEKYTPPEEMDPQYWYNIADE--EITKRLQLPQPNSQKAKNIIMFLGDGMPLSTVA 104
            :|:.|..|     .|.||.:|.:|...|.:  .:.|:|   ||....|||:|:||||||.:.||.
  Rat    13 RLQLSLSV-----IPVEEENPAFWNQKAADALNVAKKL---QPIQTSAKNLIIFLGDGMGVPTVT 69

  Fly   105 AARILKGQRQGNTGEESSLSFERFPYTGLSRTYCSNAQVPDSACTATAYLCGVKTNIVNIGVSAA 169
            |.||||||.:||.|.|:.|:.:.|||..||:||..:.||||||.||||||||||||...||||||
  Rat    70 ATRILKGQLEGNLGPETPLAMDHFPYMALSKTYSVDRQVPDSASTATAYLCGVKTNYKTIGVSAA 134

  Fly   170 VEYNNCTASQDPANRLTSIAEWAQNAGKSTGIVTTTTLTHASPSGAYAKTANRMWECDTDVTSYG 234
            ..::.|..:.  .|.:.|:...|:.||||.|:||||.:.||||:|.|..|.||.|..|.|:.:..
  Rat   135 ARFDQCNTTF--GNEVLSVMYRAKKAGKSVGVVTTTRVQHASPAGTYVHTVNRNWYGDADMPASA 197

  Fly   235 VDANSCIDMATQLVTQTPGKNFEVMFGGGMGKFLPNSIVDSH-----GNPGERSDGVNLLSRWQG 294
            :. ..|.|:|||||:   ..:..|:.|||.....|....|..     ...|.|.||.||:..|..
  Rat   198 LQ-EGCKDIATQLVS---NMDINVILGGGRKYMFPAGTPDPEYPNDVNETGTRLDGKNLVQEWLS 258

  Fly   295 LHDGGVLVTNRNQLLKLNVS-AVSSVIGLFQSKLMNFHLEADDTYQPTLSELTEVTIKKLSQNKE 358
            .|.|...|.||.:|::.::. :|:.::|||:.....|.::.|....|:|.::||..:..||:|.:
  Rat   259 KHQGSQYVWNRQELIQKSLDPSVTYLMGLFEPVDTKFEIQRDPLMDPSLKDMTEAALHVLSRNPK 323

  Fly   359 HGYFAFIEGGLIDYGNHYTKAGYALDEALEFEKAIQLARDMTDIEDTLIVVTADHGHAVSIAGYP 423
             |::.|:|||.||.|:|...|..||.||:.|:.||:.|..:|..:|||.:|||||.|..|..||.
  Rat   324 -GFYLFVEGGRIDRGHHLGTAYLALTEAVMFDSAIERASQLTSEQDTLTIVTADHSHVFSFGGYT 387

  Fly   424 GRGTPILGINQHDTDINGVQYSVLNYAAGPNQYLDENGQRIPLDDILGSDDAITPSY-----IPK 483
            .|||.|.|:...:. ::|..|:.:.|..||. |:. .|:|..:.|....|    |||     :|.
  Rat   388 LRGTSIFGLAPLNA-LDGKPYTSILYGNGPG-YVG-TGERPNVTDAESHD----PSYQQQAAVPV 445

  Fly   484 DQGVHSGEDVGIFASGPQSHLFTGVMQQSTIPHLMAYAACI 524
            ....|.||||.|||.|||:||..||.:|:.|.|:||:|.|:
  Rat   446 KSETHGGEDVAIFARGPQAHLLHGVQEQNYIAHVMAFAGCL 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alp8	NP_611655.1	ALP_like	88..525	CDD:474031	190/448 (42%)
Akp3	NP_073171.2	Alk_phosphatase	52..486	CDD:395188	190/447 (43%)