DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Alp8 and SPBC14F5.13c

DIOPT Version :9

Sequence 1:	NP_001286709.1	Gene:	Alp8 / 37540	FlyBaseID:	FBgn0034712	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_596739.1	Gene:	SPBC14F5.13c / 2539926	PomBaseID:	SPBC14F5.13c	Length:	532	Species:	Schizosaccharomyces pombe

Alignment Length:	477	Identity:	126/477 - (26%)
Similarity:	199/477 - (41%)	Gaps:	88/477 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    84 SQKAKNIIMFLGDGMPLSTVAAARILKGQRQGNTGEESSLSFERFP----YTGLSRTYCSNAQVP 144
            ::|.|.:||.:.|||...:::..|..........|       .|.|    ..|.|||..|::.:.
pombe    56 NEKPKFVIMMVSDGMGPGSLSMTRSFVETLNDKEG-------YRLPLDEHLIGSSRTRSSSSLIT 113

  Fly   145 DSACTATAYLCGVKTNIVNIGVSAAVEYNNCTASQDPANRLTSIAEWAQNAGKSTGIVTTTTLTH 209
            |||..|||:.|..||            ||......|......:|.|.|:.||..||||.|:.:|.
pombe   114 DSAAGATAFSCANKT------------YNGAVGVLDNEKPCGTILEAAKEAGYLTGIVVTSRVTD 166

  Fly   210 ASPSGAYAKTANRMWECDTDVTSYGVDANSCIDMATQLVTQTP-GKNFEVMFGGGMGKFLPNSIV 273
            |:|:...|..|||..:   |:            :|...|...| |::.:::||||:..|||.|..
pombe   167 ATPASFSAHAANRFMQ---DL------------IAEYQVGMGPLGRSVDLLFGGGLCSFLPKSTY 216

  Fly   274 DSHGNPGERSDGVNLLSRWQGLHDGGVLVTNRNQLLKLNVSAVSSVIGLFQSKLMNFHLEADDTY 338
            .|.     |||.::|| ::....:|..::.||....:|: :|...::|||.    ::||..|..|
pombe   217 RSC-----RSDNLDLL-KYARKKEGFQILLNRTDFDELS-NAQLPLLGLFS----DYHLSYDIDY 270

  Fly   339 ----QPTLSELTE----VTIKKLSQNKEHGYFAFIEGGLIDYGNHYTKAGYALDEALEFEKAIQL 395
                ||.|||:.|    |.:...:::...|:|..|||..||..:|.......:.|.:|:.:|.::
pombe   271 QPEVQPKLSEMVETALDVLLNATNEDTSKGFFLLIEGSRIDMASHNNDPIAHVYEVMEYNRAFEI 335

  Fly   396 ARDMTDIEDTLIVVTADH-------GHAVSIAGYPGR--GTPILGINQHDTD------INGVQYS 445
            |....:.....::.|:||       |..|| ..||..  ...:|.:..|..:      :|..|.:
pombe   336 ASAFVEKNGGSLISTSDHETGGLTVGRQVS-KKYPEYLWKPQVLSLALHSIEYLASAIVNHNQNT 399

  Fly   446 VLNY-------AAG-----PNQYLDENGQRIPLDDILG--SDDAITPSYIPKDQGVHSGEDVGIF 496
            :|.|       |.|     |.|..|....|..:.:::.  ||.....:.|......|:..||.::
pombe   400 LLPYIEQFVLPAIGIPDPNPKQIHDIYVARHNIFNLINVLSDIVSVEAQIGWTTHGHTAVDVNVY 464

  Fly   497 ASGPQSHLFTGVMQQSTIPHLM 518
            ..|..:....|.|:...|...|
pombe   465 GVGEVTEHLRGNMENIEIGQFM 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Alp8	NP_001286709.1	ALP_like	88..525	CDD:304875	125/473 (26%)
SPBC14F5.13c	NP_596739.1	PhoA	3..495	CDD:224699	126/477 (26%)
SPBC14F5.13c	NP_596739.1	ALP_like	60..487	CDD:304875	125/473 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	124	1.000	Domainoid score	I1405
eggNOG	1	0.900	-	-		E1_COG1785
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	124	1.000	Inparanoid score	I1462
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000192
OrthoInspector	1	1.000	-	-		otm46986
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11596
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X159
TreeFam	0	0.000	Not matched by this tool.
	9	8.960