Protein Alignment Alp8 and Alpi

DIOPT Version :10

• Sequence 1: NP_611655.1
• Gene: Alp8 / 37540
• FlyBaseID: FBgn0034712
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_073156.3
• Gene: Alpi / 24197
• RGDID: 2099
• Length: 540
• Species: Rattus norvegicus
• Alignment Length: 482
• Identity: 201/482 - (41%)
• Similarity: 282/482 - (58%)
• Gaps: 29/482 - (6%)

  Fly    56 PPEEMDPQYWYNIADE--EITKRLQLPQPNSQKAKNIIMFLGDGMPLSTVAAARILKGQRQGNTG 118
            |.||.:|.:|...|.|  ::.|:|   ||....|||:|:||||||.:.||.|.||||||..|:.|
  Rat    23 PVEEENPVFWNQKAKEALDVAKKL---QPIQTSAKNLILFLGDGMGVPTVTATRILKGQLGGHLG 84

  Fly   119 EESSLSFERFPYTGLSRTYCSNAQVPDSACTATAYLCGVKTNIVNIGVSAAVEYNNCTASQDPAN 183
            .|:.|:.:.||:|.||:||..:.||||||.||||||||||.|...||||||..:|.|.::.  .|
  Rat    85 PETPLAMDHFPFTALSKTYNVDRQVPDSAGTATAYLCGVKANYKTIGVSAAARFNQCNSTF--GN 147

  Fly   184 RLTSIAEWAQNAGKSTGIVTTTTLTHASPSGAYAKTANRMWECDTDVTSYGVDANSCIDMATQLV 248
            .:.|:...|:.||||.|:||||.:.||||:|.||.|.||.|..|.|:.|..:. ..|.|:||||:
  Rat   148 EVFSVMHRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRDWYSDADMPSSALQ-EGCKDIATQLI 211

  Fly   249 TQTPGKNFEVMFGGGMGKFLPNSIVDSHGNPGE------RSDGVNLLSRWQGLHDGGVLVTNRNQ 307
            :   ..:.:|:.|||.....|....|.. .||:      |.|..||:..|...:.|...|.||.|
  Rat   212 S---NMDIDVILGGGRKFMFPKGTPDPE-YPGDSDQSGVRLDSRNLVEEWLAKYQGTRYVWNREQ 272

  Fly   308 LLKLNVS-AVSSVIGLFQSKLMNFHLEADDTYQPTLSELTEVTIKKLSQNKEHGYFAFIEGGLID 371
            |::.:.. ||:.::|||:...|.:.:..:.:..|:|:|:|||.::.||:|.: |::.|:|||.||
  Rat   273 LMQASQDPAVTRLMGLFEPAEMKYDVNRNASADPSLAEMTEVAVRLLSRNPQ-GFYLFVEGGRID 336

  Fly   372 YGNHYTKAGYALDEALEFEKAIQLARDMTDIEDTLIVVTADHGHAVSIAGYPGRGTPILG---IN 433
            .|:|...|..||.||:.|:.||:.|..:|:.:|||.::||||.|..:..||..|||.|.|   :|
  Rat   337 QGHHAGTAYLALTEAVMFDSAIEKASQLTNEKDTLTLITADHSHVFAFGGYTLRGTSIFGLAPLN 401

  Fly   434 QHDTDINGVQYSVLNYAAGPNQYLDENGQRIPLDDILGSD-DAITPSYIPKDQGVHSGEDVGIFA 497
            ..|    |..|:.:.|..||. |:..:|.|..:.|....| :....:.:|.....|.||||.|||
  Rat   402 AQD----GKSYTSILYGNGPG-YVLNSGNRPNVTDAESGDVNYKQQAAVPLSSETHGGEDVAIFA 461

  Fly   498 SGPQSHLFTGVMQQSTIPHLMAYAACI 524
            .|||:||..||.:|:.|.|:||:|.|:
  Rat   462 RGPQAHLVHGVQEQNYIAHVMAFAGCL 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alp8	NP_611655.1	ALP_like	88..525	CDD:474031	189/448 (42%)
Alpi	NP_073156.3	Alk_phosphatase	53..488	CDD:395188	189/447 (42%)