DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Alp8 and arnt2

DIOPT Version :9

Sequence 1:	NP_001286709.1	Gene:	Alp8 / 37540	FlyBaseID:	FBgn0034712	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	XP_012813827.1	Gene:	arnt2 / 100101693	XenbaseID:	XB-GENE-487404	Length:	723	Species:	Xenopus tropicalis

Alignment Length:	240	Identity:	53/240 - (22%)
Similarity:	84/240 - (35%)	Gaps:	49/240 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   121 SSLSFERFPYTG-LSRTYCSNAQVPDSACTATAYLCGVKTNIVNIGVSAAVEYNNCTASQDPANR 184
            ||.:|:. ||:. :....|:|..|..           |:.....:.|......::...||.|
Frog   423 SSFTFQN-PYSDEIEYIICTNTNVKQ-----------VQQQQAELEVHPRDSLSSYDLSQVP--- 472

  Fly   185 LTSIAEWAQNAGKSTGIVTTTTLTHASPSGAYAKTAN-RMWECDTDVTSYGVDANSCIDMATQLV 248
            :.::|......|||  :|.       .|...:::..: |..|....:|:......|.....||.:
Frog   473 VPNLAANVHEGGKS--VVD-------KPDPIFSQDRDPRFAEMFAGITASEKKMLSASGSGTQQL 528

  Fly   249 TQTPGKNFEVMFGGGMGKFLPNSIVDSHG-----NPGERSDGVNLLSRWQGLHDGGVLVTNR--- 305
            ..| |..|:   .|..||...:|:|...|     :|.  :.|.||....:.::.|.|...:|
Frog   529 YST-GSPFQ---PGHSGKSFSSSVVHVTGVNEIQSPS--ATGQNLTQISRQMNAGQVWTGSRPPF 587

  Fly   306 --NQLLKLNVSAVSSVIGLFQSKLMNFHLEADD--TYQPTLSELT 346
              .|:........||..|:..|     |....|  ||.|..|..|
Frog   588 QGQQIASQTSKPQSSPFGIGTS-----HTYTSDPSTYSPLSSPAT 627

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Alp8	NP_001286709.1	ALP_like	88..525	CDD:304875	53/240 (22%)
arnt2	XP_012813827.1	HLH	72..124	CDD:278439
		PAS	144..250	CDD:279347
		PAS	147..206	CDD:214512
		PAS_11	343..443	CDD:291273	6/20 (30%)
		PAS	343..439	CDD:238075	5/16 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1785
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900