Protein Alignment Alp2 and Alpi

DIOPT Version :9

• Sequence 1: NP_611654.1
• Gene: Alp2 / 37539
• FlyBaseID: FBgn0283480
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_001074551.1
• Gene: Alpi / 76768
• MGIID: 1924018
• Length: 554
• Species: Mus musculus
• Alignment Length: 481
• Identity: 200/481 - (41%)
• Similarity: 279/481 - (58%)
• Gaps: 28/481 - (5%)

  Fly    57 PPEEMDPQFWYKLADE--EIAKRLQLPQPNSDRAKNVIMFLGDGMPISTVTAARILKGQRQGNTG 119
            |.||.:|.||.|.|.|  :.||:|   ||....|||:|:||||||.:.||||.||||||.:|:.|
Mouse    23 PAEEENPAFWNKKAAEALDAAKKL---QPIQTSAKNLIIFLGDGMGVPTVTATRILKGQLEGHLG 84

  Fly   120 EESSLSFEKFPYSGLSRTYCANAQVPDSACTATAYLCGVKTNIINIGVSAAVNFNNCTASQDPAN 184
            .|:.|:.:.|||..||:||..:.||||||.||||||||||.|...||:|||...:.|..:.  .|
Mouse    85 PETPLAMDLFPYMALSKTYNVDRQVPDSAGTATAYLCGVKANYKTIGLSAAARLDQCNTTF--GN 147

  Fly   185 RLTSIAEWAQNAGKSTGFVTTTTLTHASPSGAYAKTANRMWQSDTDVTSYGVDASTCVDMATQLV 249
            .:.|:...|:.||||.|.||||.:.||||:|.||.|.||.|.||.::.:..:. ..|.|:||||:
Mouse   148 EVFSVMYRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRNWYSDAEMPASALQ-DGCKDIATQLI 211

  Fly   250 TQTPGKNFEVMFGGGMGKFLPKTTKD-----SHGKYGERSDGVNLLSRWQGLHDKGVLVTNRKQL 309
            :   ..:.:|:.|||.....||.|.|     ...:.|.|.|..||:..|...|.....|.||.:|
Mouse   212 S---NMDIDVILGGGRKFMFPKGTPDPEYPSDSNQSGTRLDDQNLVQTWLSKHQGARYVWNRSEL 273

  Fly   310 LNLDVS-AASSIIGTFQSGLMDFHMDADPTYQPTLSELTEVAIKKLSHNENGYFVFIEGGLIDYG 373
            :..... |.:.::|.|:...|.:..:.:|:..|:|:|:||||::.||.|..|:::|:|||.||.|
Mouse   274 IQASQDPAVTHLMGLFEPTEMKYDANRNPSVDPSLAEMTEVAVRMLSRNPQGFYLFVEGGRIDQG 338

  Fly   374 NHYTQAGYALDEALEFEKAIQLAREMTNISDTLIVVTADHGHAVSIAGYPGRGTPILGLNQHDTD 438
            :|...|..||.||:.|:.||:.|.::||..||||::||||.|..:..||..|||.|.||.....
Mouse   339 HHAGTAYLALTEAVMFDSAIEKASQLTNEKDTLILITADHSHVFAFGGYTLRGTSIFGLAPLKA- 402

  Fly   439 INGVKYSVLNYAAGPNQYLDEHGQRIPLDDILGPDDAISPSY-----IDKEIGVHSGEDVGIWAS 498
            ::...|:.:.|..||...| :.|.|..:.:.    .::.|:|     :......|.||||.|:|.
Mouse   403 LDDKSYTSILYGNGPGYEL-KSGNRPNVTEA----QSVDPNYKQQAAVPLSSETHGGEDVAIFAR 462

  Fly   499 GPQSHLFTGVMQQSTIPHLMAYASCV 524
            |||:||..||.:|:.|.|:||:|.|:
Mouse   463 GPQAHLVHGVQEQNYIAHVMAFAGCL 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alp2	NP_611654.1	ALP_like	89..525	CDD:304875	185/447 (41%)
Alpi	NP_001074551.1	Alk_phosphatase	53..488	CDD:278666	185/446 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847898
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1785
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48882
OrthoDB	1	1.010	-	-		D216917at33208
OrthoFinder	1	1.000	-	-		FOG0000192
OrthoInspector	1	1.000	-	-		mtm8903
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X159
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.760