Protein Alignment Alp2 and Alppl2

DIOPT Version :9

• Sequence 1: NP_611654.1
• Gene: Alp2 / 37539
• FlyBaseID: FBgn0283480
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_031459.3
• Gene: Alppl2 / 11650
• MGIID: 108009
• Length: 529
• Species: Mus musculus
• Alignment Length: 481
• Identity: 196/481 - (40%)
• Similarity: 290/481 - (60%)
• Gaps: 28/481 - (5%)

  Fly    57 PPEEMDPQFWYKLADE--EIAKRLQLPQPNSDRAKNVIMFLGDGMPISTVTAARILKGQRQGNTG 119
            |.||.:|.||.:.|.|  :.||:|   :|....|||:::.:||||.:|||||.||||||:||:.|
Mouse    21 PVEEENPAFWNRKAAEALDAAKKL---KPIQTSAKNLVILMGDGMGVSTVTATRILKGQQQGHLG 82

  Fly   120 EESSLSFEKFPYSGLSRTYCANAQVPDSACTATAYLCGVKTNIINIGVSAAVNFNNCTASQDPAN 184
            .|:.|:.::||:..||:||..:.|:||||.|.||:|||||||:..||:|||..||.|..:.  .|
Mouse    83 PETQLAMDRFPHMALSKTYNTDKQIPDSAGTGTAFLCGVKTNMKVIGLSAAARFNQCNTTW--GN 145

  Fly   185 RLTSIAEWAQNAGKSTGFVTTTTLTHASPSGAYAKTANRMWQSDTDVTSYGVDASTCVDMATQLV 249
            .:.|:...|:.||||.|.||||::.||||:|.||.|.||.|.||..:.:..:. ..|.|::|||:
Mouse   146 EVVSVMHRAKKAGKSVGVVTTTSVQHASPAGTYAHTVNRGWYSDAQMPASALQ-DGCKDISTQLI 209

  Fly   250 TQTPGKNFEVMFGGGMGKFLPKTTKDSH-----GKYGERSDGVNLLSRWQGLHDKGVLVTNRKQL 309
            :   ..:.:|:.|||.....||.|.|..     .:.|.|.||.||:..|...|.....|.||.:|
Mouse   210 S---NMDIDVILGGGRKFMFPKGTPDQEYPTDTKQAGTRLDGRNLVQEWLAKHQGARYVWNRSEL 271

  Fly   310 LNLDVS-AASSIIGTFQSGLMDFHMDADPTYQPTLSELTEVAIKKLSHNENGYFVFIEGGLIDYG 373
            :...:: :.:.::|.|:...|.:.:..||...|:|:|:||||::.||.|..|:::|:|||.||:|
Mouse   272 IQASLNRSVTHLMGLFEPNDMKYEIHRDPAQDPSLAEMTEVAVRMLSRNPKGFYLFVEGGRIDHG 336

  Fly   374 NHYTQAGYALDEALEFEKAIQLAREMTNISDTLIVVTADHGHAVSIAGYPGRGTPILGLNQHDTD 438
            :|.|.|..||.||:.|:.|:..|.::|:..||:|:|||||.|..|..||..||..|.||.....:
Mouse   337 HHETVAYRALTEAVMFDSAVDKADKLTSEQDTMILVTADHSHVFSFGGYTQRGASIFGLAPFKAE 401

  Fly   439 INGVKYSVLNYAAGPNQYLDEHGQRIPLDDILGPDDAISPSY-----IDKEIGVHSGEDVGIWAS 498
             :|..::.:.|..||. |...:|.|..:.:    :::.:|:|     :......||||||.|:|.
Mouse   402 -DGKSFTSILYGNGPG-YKLHNGARADVTE----EESSNPTYQQQAAVPLSSETHSGEDVAIFAR 460

  Fly   499 GPQSHLFTGVMQQSTIPHLMAYASCV 524
            |||:||..||.:|:.|.|:||:|:|:
Mouse   461 GPQAHLVHGVQEQNYIAHVMAFAACL 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alp2	NP_611654.1	ALP_like	89..525	CDD:304875	183/447 (41%)
Alppl2	NP_031459.3	Alk_phosphatase	51..486	CDD:333956	183/446 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847859
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1785
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H129600
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48882
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000192
OrthoInspector	1	1.000	-	-		mtm8903
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X159
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.750