Protein Alignment Alp2 and Alpp

DIOPT Version :10

• Sequence 1: NP_611654.1
• Gene: Alp2 / 37539
• FlyBaseID: FBgn0283480
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: XP_002730104.3
• Gene: Alpp / 100359675
• RGDID: 2325055
• Length: 529
• Species: Rattus norvegicus
• Alignment Length: 481
• Identity: 200/481 - (41%)
• Similarity: 289/481 - (60%)
• Gaps: 28/481 - (5%)

  Fly    57 PPEEMDPQFWYKLADE--EIAKRLQLPQPNSDRAKNVIMFLGDGMPISTVTAARILKGQRQGNTG 119
            |.||.:|.||.:.|.|  |.||:|   ||....|.|:|:.:||||.:|||||.||||||:||:.|
  Rat    21 PVEEENPAFWNRKAAEALEAAKKL---QPIQTSANNLIILMGDGMGVSTVTATRILKGQQQGHLG 82

  Fly   120 EESSLSFEKFPYSGLSRTYCANAQVPDSACTATAYLCGVKTNIINIGVSAAVNFNNCTASQDPAN 184
            .|:.|:.::||:..||:||..:.||||||.|.||:|||||||:..||:|||..||.|..:.  .|
  Rat    83 PETPLAMDRFPHMALSKTYNTDKQVPDSAGTGTAFLCGVKTNMKVIGLSAAARFNQCNTTW--GN 145

  Fly   185 RLTSIAEWAQNAGKSTGFVTTTTLTHASPSGAYAKTANRMWQSDTDVTSYGVDASTCVDMATQLV 249
            .:.|:...|:.||||.|.||||::.||||:|.||.|.||.|.||..:::..:... |.|:|.||:
  Rat   146 EVVSVMHRAKKAGKSVGVVTTTSVQHASPAGTYAHTVNRNWYSDAHMSTAALQEG-CKDIAMQLI 209

  Fly   250 TQTPGKNFEVMFGGGMGKFLPKTTKDSH-----GKYGERSDGVNLLSRWQGLHDKGVLVTNRKQL 309
            :.|   :.:|:.|||.....||.|.|..     .:.|.|.||.||:..|...|.....|.||.:|
  Rat   210 SNT---DIDVILGGGRKFMFPKGTPDQEYPTDPQQAGTRLDGRNLVQEWLAKHQGAQYVWNRTEL 271

  Fly   310 LNLDVS-AASSIIGTFQSGLMDFHMDADPTYQPTLSELTEVAIKKLSHNENGYFVFIEGGLIDYG 373
            :...:: :.:.::|.|:...|.:::|.|||..|:|:|:||||:..||.|..|:::|:|||.||:|
  Rat   272 IQASLNRSVTHLMGLFEPNDMKYNIDRDPTQDPSLAEMTEVAVHMLSRNPKGFYLFVEGGRIDHG 336

  Fly   374 NHYTQAGYALDEALEFEKAIQLAREMTNISDTLIVVTADHGHAVSIAGYPGRGTPILGLNQHDTD 438
            :|...|..||.||:.|:.|:..|.::|:..||:|:|||||.|..|..||..|...|.||......
  Rat   337 HHEAIAYRALTEAVMFDSAVDKADKLTSEKDTMIIVTADHSHVFSFGGYTQREASIFGLAPFKAG 401

  Fly   439 INGVKYSVLNYAAGPNQYLDEHGQRIPLDDILGPDDAISPSY-----IDKEIGVHSGEDVGIWAS 498
             :|..::.:.|..||...|: :|.|..:.:    :::.:|:|     :......||||||.|:|.
  Rat   402 -DGKSFTSILYGNGPGYKLN-NGIRADVTE----EESSNPTYQQQAAVPLSSETHSGEDVAIFAR 460

  Fly   499 GPQSHLFTGVMQQSTIPHLMAYASCV 524
            |||:||..||.:|:.|.|:||:|.|:
  Rat   461 GPQAHLVHGVQEQNYIAHVMAFAGCL 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alp2	NP_611654.1	ALP_like	89..525	CDD:474031	185/447 (41%)
Alpp	XP_002730104.3	Alk_phosphatase	51..486	CDD:395188	185/446 (41%)