Protein Alignment Alp7 and PHO8

DIOPT Version :10

• Sequence 1: NP_611653.1
• Gene: Alp7 / 37538
• FlyBaseID: FBgn0034710
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_010769.3
• Gene: PHO8 / 852092
• SGDID: S000002889
• Length: 566
• Species: Saccharomyces cerevisiae
• Alignment Length: 474
• Identity: 132/474 - (27%)
• Similarity: 197/474 - (41%)
• Gaps: 105/474 - (22%)

  Fly    92 KAKNVILFLGDGMSLSTVAAARIHKGQLKGNTGEEDSLSFEKFPYTGLSRTYCSNAQVPDSACTA 156
            |.||||.|:.|||..::::.||.. .|...:...:|.|:.::. :.|.|||..|::.|.|||..|
Yeast    65 KKKNVIFFVTDGMGPASLSMARSF-NQHVNDLPIDDILTLDEH-FIGSSRTRSSDSLVTDSAAGA 127

  Fly   157 TAYLCGVKTNIVALGITAAVSFNNCSGSEDPANQVDSIAAWAQAAGKATGIVTTTTLTHASPSGA 221
            ||:.|.:|            |:|...|.:.......::...|:.||..||:|.||.:|.|:|:.
Yeast   128 TAFACALK------------SYNGAIGVDPHHRPCGTVLEAAKLAGYLTGLVVTTRITDATPAS- 179

  Fly   222 YAKTTNRFFESDTDILTYGEGQNDPATCTDIATQLITQAP-GKNFDVMLGGGIGKFLP-NTITDP 284
                    |.|..|.    ..|.|.     |||..:.:.| |:..|:::|||...|.| .....|
Yeast   180 --------FSSHVDY----RWQEDL-----IATHQLGEYPLGRVVDLLMGGGRSHFYPQGEKASP 227

  Fly   285 FNKKGERSDGVNLLSR-----WQGLHPGGVLAYNRNQLLSVNVSKIT-NLIGTFRSGVMSFNKMA 343
            :...|.|.||.:|:..     ||  :.|.  ..|.:.||..:...:| ..:|.|....:.|....
Yeast   228 YGHHGARKDGRDLIDEAQSNGWQ--YVGD--RKNFDSLLKSHGENVTLPFLGLFADNDIPFEIDR 288

  Fly   344 DPKEEPTLAEMTR---KAIEVVSKRD---GGYFLFVEGGLIDYGNHFNSPTYSLSETLQFEQAVQ 402
            |.||.|:|.|..:   .|:|..|..|   .|:||.|||..||:..|.|.|...:.|.|.|::|.|
Yeast   289 DEKEYPSLKEQVKVALGALEKASNEDKDSNGFFLMVEGSRIDHAGHQNDPASQVREVLAFDEAFQ 353

  Fly   403 EALDITD--PEETLIVVTSDH-------------AHP-----------LTISG------------ 429
            ..|:..:  ..||::|.||||             ::|           .|.||
Yeast   354 YVLEFAENSDTETVLVSTSDHETGGLVTSRQVTASYPQYVWYPQVLANATHSGEFLKRKLVDFVH 418

  Fly   430 -YPGRGTPILGLNQDDTDVNGVKYATLNYAVGTNQYLDEHGQR-IDLTDQIGA-EDFIHP----- 486
             :.|..:.|         .|.:|:..|...:|...|.|...:. |.|.|...| :|.::.
Yeast   419 EHKGASSKI---------ENFIKHEILEKDLGIYDYTDSDLETLIHLDDNANAIQDKLNDMVSFR 474

  Fly   487 SYIHGTIGVHAGDDVGIFA 505
            :.|..|...|:..||.|:|
Yeast   475 AQIGWTTHGHSAVDVNIYA 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alp7	NP_611653.1	ALP_like	94..533	CDD:474031	131/472 (28%)
PHO8	NP_010769.3	Alk_phosphatase	66..527	CDD:395188	131/473 (28%)