DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Alp7 and Akp3

DIOPT Version :9

Sequence 1:	NP_611653.1	Gene:	Alp7 / 37538	FlyBaseID:	FBgn0034710	Length:	543	Species:	Drosophila melanogaster
Sequence 2:	NP_073171.2	Gene:	Akp3 / 64621	RGDID:	621650	Length:	558	Species:	Rattus norvegicus

Alignment Length:	509	Identity:	203/509 - (39%)
Similarity:	286/509 - (56%)	Gaps:	58/509 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 PEEEKNAQFWYDLAYE--EIAKRLEQPQLDKRKAKNVILFLGDGMSLSTVAAARIHKGQLKGNTG 124
            |.||:|..||...|.:  .:||:|:..|   ..|||:|:||||||.:.||.|.||.||||:||.|
  Rat    22 PVEEENPAFWNQKAADALNVAKKLQPIQ---TSAKNLIIFLGDGMGVPTVTATRILKGQLEGNLG 83

  Fly   125 EEDSLSFEKFPYTGLSRTYCSNAQVPDSACTATAYLCGVKTNIVALGITAAVSFNNCSGSEDPAN 189
            .|..|:.:.|||..||:||..:.||||||.||||||||||||...:|::||..|:.|:.:.  .|
  Rat    84 PETPLAMDHFPYMALSKTYSVDRQVPDSASTATAYLCGVKTNYKTIGVSAAARFDQCNTTF--GN 146

  Fly   190 QVDSIAAWAQAAGKATGIVTTTTLTHASPSGAYAKTTNRFFESDTDILTYGEGQNDPAT-----C 249
            :|.|:...|:.|||:.|:||||.:.||||:|.|..|.||.:..|.|:         ||:     |
  Rat   147 EVLSVMYRAKKAGKSVGVVTTTRVQHASPAGTYVHTVNRNWYGDADM---------PASALQEGC 202

  Fly   250 TDIATQLITQAPGKNFDVMLGGGIGKFLPNTITDP-----FNKKGERSDGVNLLSRWQGLHPGGV 309
            .||||||::   ..:.:|:||||.....|....||     .|:.|.|.||.||:..|...|.|..
  Rat   203 KDIATQLVS---NMDINVILGGGRKYMFPAGTPDPEYPNDVNETGTRLDGKNLVQEWLSKHQGSQ 264

  Fly   310 LAYNRNQLLSVNVS-KITNLIGTFRSGVMSFNKMADPKEEPTLAEMTRKAIEVVSKRDGGYFLFV 373
            ..:||.:|:..::. .:|.|:|.|......|....||..:|:|.:||..|:.|:|:...|::|||
  Rat   265 YVWNRQELIQKSLDPSVTYLMGLFEPVDTKFEIQRDPLMDPSLKDMTEAALHVLSRNPKGFYLFV 329

  Fly   374 EGGLIDYGNHFNSPTYSLSETLQFEQAVQEALDITDPEETLIVVTSDHAHPLTISGYPGRGTPIL 438
            |||.||.|:|..:...:|:|.:.|:.|::.|..:|..::||.:||:||:|..:..||..|||.|.
  Rat   330 EGGRIDRGHHLGTAYLALTEAVMFDSAIERASQLTSEQDTLTIVTADHSHVFSFGGYTLRGTSIF 394

  Fly   439 GLNQDDTDVNGVKYATLNYA-----VGTNQYLDEHGQRIDLTDQIGAEDFIHPSY-----IHGTI 493
            ||...:. ::|..|.::.|.     |||       |:|.::||   ||.. .|||     :....
  Rat   395 GLAPLNA-LDGKPYTSILYGNGPGYVGT-------GERPNVTD---AESH-DPSYQQQAAVPVKS 447

  Fly   494 GVHAGDDVGIFATGPQSHLFTGVMQQSTIPHLMAYASCI------GNGPTLCDN 541
            ..|.|:||.|||.|||:||..||.:|:.|.|:||:|.|:      |..|...:|
  Rat   448 ETHGGEDVAIFARGPQAHLLHGVQEQNYIAHVMAFAGCLEPYTDCGLAPPADEN 501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Alp7	NP_611653.1	ALP_like	94..533	CDD:304875	188/465 (40%)
Akp3	NP_073171.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351417
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48882
OrthoDB	1	1.010	-	-		D216917at33208
OrthoFinder	1	1.000	-	-		FOG0000192
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X159
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.860