Protein Alignment Swim and CTSF

DIOPT Version :9

• Sequence 1: NP_611652.2
• Gene: Swim / 37537
• FlyBaseID: FBgn0034709
• Length: 431
• Species: Drosophila melanogaster
• Sequence 2: NP_003784.2
• Gene: CTSF / 8722
• HGNCID: 2531
• Length: 484
• Species: Homo sapiens
• Alignment Length: 253
• Identity: 66/253 - (26%)
• Similarity: 105/253 - (41%)
• Gaps: 42/253 - (16%)

  Fly   168 KEPTYRVKAMTRLKNPTDGLPSSFNALDKWSS--YISEVPDQGWCGASWVLSTT-SVASDRFAIQ 229
            |||..::|   :.|:..|..|..::    |.|  .:::|.|||.||:.|..|.| :|....|..|
Human   255 KEPGNKMK---QAKSVGDLAPPEWD----WRSKGAVTKVKDQGMCGSCWAFSVTGNVEGQWFLNQ 312

  Fly   230 SKGKENVQLSAQNILSCTRRQQGCEGGHLDAAWRYLHKKGVVD-ENCYPYTQHRDTCKIRHNSRS 293
            .   ..:.||.|.:|.|.:..:.|.||....|:..:...|.:: |:.|.|..|..:|..
Human   313 G---TLLSLSEQELLDCDKMDKACMGGLPSNAYSAIKNLGGLETEDDYSYQGHMQSCNF------ 368

  Fly   294 LRANGCQKPVNVDRDSLYTVGPAYSLNREADIMAEIFHSGPVQATMRVNRDFFAYSGGVYRETAA 358
                      :.::..:|..........|..:.|.:...||:...:.      |:....||...:
Human   369 ----------SAEKAKVYINDSVELSQNEQKLAAWLAKRGPISVAIN------AFGMQFYRHGIS 417

  Fly   359 NRKAPTGF-----HSVKLVGWGEEHNGEKYWIAANSWGSWWGEHGYFRILRGSNECGI 411
            ....|...     |:|.|||:| ..:...:|...||||:.|||.||:.:.|||..||:
Human   418 RPLRPLCSPWLIDHAVLLVGYG-NRSDVPFWAIKNSWGTDWGEKGYYYLHRGSGACGV 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Swim	NP_611652.2	Somatomedin_B	41..83	CDD:279385
		VWC	91..>126	CDD:302663
		Peptidase_C1A_CathepsinB	188..417	CDD:239111	60/233 (26%)
CTSF	NP_003784.2	Inhibitor_I29	187..243	CDD:214853
		Peptidase_C1	271..482	CDD:278538	60/234 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149684
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930