Protein Alignment Swim and ctsbb

DIOPT Version :10

• Sequence 1: NP_611652.2
• Gene: Swim / 37537
• FlyBaseID: FBgn0034709
• Length: 431
• Species: Drosophila melanogaster
• Sequence 2: NP_001418075.1
• Gene: ctsbb / 569298
• ZFINID: ZDB-GENE-070323-1
• Length: 326
• Species: Danio rerio
• Alignment Length: 348
• Identity: 116/348 - (33%)
• Similarity: 168/348 - (48%)
• Gaps: 79/348 - (22%)

  Fly   118 SVQCDEDLCLTDDAIVHSVNSIHRLGWSA--------RKYDQWWGRKYSEGLKLRLGT--KEP-- 170
            ||.|......|.|.::..:|:. |..|:|        :||           ||...||  |.|
Zfish    11 SVTCARPQLHTHDEMISFINAA-RSTWTAGVNFDNVPKKY-----------LKSLCGTVLKGPRL 63

  Fly   171 TYRVKAMTRLKNPTDGLPSSFNALDKWSS--YISEVPDQGWCGASWVLSTTSVASDRFAIQSKGK 233
            .:.||..|.:|     ||.||:..|:|.:  .::::.|||.||:.|........|||..|.||||
Zfish    64 PHTVKHSTNVK-----LPDSFDLRDQWPNCKTLNQIRDQGSCGSCWAFGAVESISDRICIHSKGK 123

  Fly   234 ENVQLSAQNILSCTRR-QQGCEGGHLDAAWRYLHKKGVV-------DENCYPYT----QHRDTCK 286
            ::.::||:::|||..: ..||.||....||.|..:.|:|       |..|.||:    :|
Zfish   124 QSPEISAEDLLSCCDQCGFGCSGGFPAEAWDYWRRSGLVTGGLYNSDVGCRPYSIAPCEH----- 183

  Fly   287 IRHNSRSLRANGCQKPVNVDRDSLYTVG---PAYSLNREAD----------------IMAEIFHS 332
                    ..||.:.|.:.::|:....|   |.||:..:.|                ||.|::.:
Zfish   184 --------HVNGTRPPCSGEQDTPKCTGVCIPKYSVPYKQDKHFGSKVYNVPSDQQQIMTELYTN 240

  Fly   333 GPVQATMRVNRDFFAYSGGVYRETAANRKAPTGFHSVKLVGWGEEHNGEKYWIAANSWGSWWGEH 397
            |||:|...|..||..|..|||:....   :..|.|:||::||||| ||..:|:.||||.|.||::
Zfish   241 GPVEAAFTVYEDFPLYKSGVYQHLTG---SALGGHAVKILGWGEE-NGTPFWLVANSWNSDWGDN 301

  Fly   398 GYFRILRGSNECGIEEYVLASWP 420
            |||:||||.:|||||..::|..|
Zfish   302 GYFKILRGHDECGIESEMVAGLP 324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Swim	NP_611652.2	Somatomedin_B	41..84	CDD:460034
		Peptidase_C1A_CathepsinB	188..417	CDD:239111	92/261 (35%)
ctsbb	NP_001418075.1	Propeptide_C1	23..60	CDD:462365	11/48 (23%)
		Peptidase_C1A_CathepsinB	76..322	CDD:239111	92/262 (35%)