Protein Alignment Swim and Cts7

DIOPT Version :10

• Sequence 1: NP_611652.2
• Gene: Swim / 37537
• FlyBaseID: FBgn0034709
• Length: 431
• Species: Drosophila melanogaster
• Sequence 2: NP_062412.1
• Gene: Cts7 / 56092
• MGIID: 1860262
• Length: 331
• Species: Mus musculus
• Alignment Length: 267
• Identity: 82/267 - (30%)
• Similarity: 130/267 - (48%)
• Gaps: 34/267 - (12%)

  Fly   160 GLKLRLGTKEPTYRVKAMTRLKNPTDGLPSSFNALDKW--SSYISEVPDQGWCGASWVLSTTSVA 222
            |.::::.|:..:|.::....::.....:|.:.:    |  ..|::.|..||.|||.|..|.|:..
Mouse    85 GEEMKMLTESSSYPLRNGKHIQKRNPKIPPTLD----WRKEGYVTPVRRQGSCGACWAFSVTACI 145

  Fly   223 SDRFAIQSKGKENVQLSAQNILSC--TRRQQGCEGGHLDAAWRYLHKKGVVD-ENCYPYTQHRDT 284
            ..:. .:..|| .:.||.||::.|  :...:||:||....|::|:...|.:: |..|||......
Mouse   146 EGQL-FKKTGK-LIPLSVQNLMDCSVSYGTKGCDGGRPYDAFQYVKNNGGLEAEATYPYEAKAKH 208

  Fly   285 CKIRHNSRSLRANGCQKPVNVDRDSLYTVGPAYSLNREADIMAEIFHSGPVQATM-RVNRDFFAY 348
            |:.| ..||:        |.|:|   :.|.|.   |.||.:.|.:.| ||:...: ..:..|.:|
Mouse   209 CRYR-PERSV--------VKVNR---FFVVPR---NEEALLQALVTH-GPIAVAIDGSHASFHSY 257

  Fly   349 SGGVYRETAANRKAPTGFHSVKLVGWG-EEHNGE--KYWIAANSWGSWWGEHGYFRILRGSNE-C 409
            .||:|.|....:  .|..|.:.|||:| |.|..|  |||:..||.|..|||:||.::.||.|. |
Mouse   258 RGGIYHEPKCRK--DTLDHGLLLVGYGYEGHESENRKYWLLKNSHGERWGENGYMKLPRGQNNYC 320

  Fly   410 GIEEYVL 416
            ||..|.:
Mouse   321 GIASYAM 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Swim	NP_611652.2	Somatomedin_B	41..84	CDD:460034
		Peptidase_C1A_CathepsinB	188..417	CDD:239111	79/239 (33%)
Cts7	NP_062412.1	Inhibitor_I29	29..87	CDD:214853	1/1 (100%)
		Nuclear localization signal. /evidence=ECO:0000269|PubMed:18776147	33..50
		Peptidase_C1A	113..329	CDD:239068	79/239 (33%)