Protein Alignment Swim and Ctsrl1

DIOPT Version :10

• Sequence 1: NP_611652.2
• Gene: Swim / 37537
• FlyBaseID: FBgn0034709
• Length: 431
• Species: Drosophila melanogaster
• Sequence 2: NP_001017509.1
• Gene: Ctsrl1 / 498688
• RGDID: 1562210
• Length: 334
• Species: Rattus norvegicus
• Alignment Length: 333
• Identity: 89/333 - (26%)
• Similarity: 126/333 - (37%)
• Gaps: 87/333 - (26%)

  Fly   151 QW--WGRKYS-----EGLKLRLGTKEPTYRVKAMTRLKNPTDGL--------------------- 187
            :|  |.:||.     |..:||....|...:   |.:|.|..:||
  Rat    28 EWQEWKKKYDKSYSLEEEELRRAVWEENLK---MIKLHNGENGLGKNGFTMEINEFGDTTGEEFR 89

  Fly   188 ----------------------PSSFNALDKW--SSYISEVPDQGWCGASWVLSTTSVASDRFAI 228
                                  .|.|.....|  ..|::.|..||.|.|.|..|.|. |.:...|
  Rat    90 KMMVEFPVQTHREGKSIMKRAAGSIFPKFVDWRKKGYVTPVRRQGNCNACWAFSVTG-AIEAQTI 153

  Fly   229 QSKGKENVQLSAQNILSCTRRQ--QGCEGGHLDAAWRY-LHKKGVVDENCYPYTQHRDTCKIRHN 290
            ...|| .:.||.||::.|::.|  .||.||....|::| ||..|:..|..|||......|:....
  Rat   154 WQSGK-LIPLSVQNLVDCSKPQGNNGCLGGDTYNAFQYVLHNGGLQSEATYPYEGKDGPCRYNPK 217

  Fly   291 SRSLRANGCQKPVNVDRDSLYTVGPAYSLNREADI-MAEIFHSGPVQATMRVNRDFFA-YSGGVY 353
            :.|....|                 ..||....|| |..:...||:.|.:..:.:.|. |..|:|
  Rat   218 NSSAEITG-----------------FVSLPESEDILMVAVATIGPISAGIDASHESFKFYKKGIY 265

  Fly   354 RETAANRKAPTGFHSVKLVGWGEEHN---GEKYWIAANSWGSWWGEHGYFRILRG-SNECGIEEY 414
            .|...:..:.|  |.|.:||:|.:.|   |:.||:..||||..||..||.:|.:. :|.|.|..|
  Rat   266 HEPNCSSNSVT--HGVLVVGYGFKGNDTGGDHYWLIKNSWGKQWGIRGYMKITKDKNNHCAIASY 328

  Fly   415 VLASWPYV 422
              |.:|.:
  Rat   329 --AHYPTI 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Swim	NP_611652.2	Somatomedin_B	41..84	CDD:460034
		Peptidase_C1A_CathepsinB	188..417	CDD:239111	74/239 (31%)
Ctsrl1	NP_001017509.1	Inhibitor_I29	29..87	CDD:214853	13/60 (22%)
		Peptidase_C1A	116..332	CDD:239068	73/238 (31%)