Protein Alignment Swim and CtsB1

DIOPT Version :9

• Sequence 1: NP_611652.2
• Gene: Swim / 37537
• FlyBaseID: FBgn0034709
• Length: 431
• Species: Drosophila melanogaster
• Sequence 2: NP_001259536.2
• Gene: CtsB1 / 32341
• FlyBaseID: FBgn0030521
• Length: 340
• Species: Drosophila melanogaster
• Alignment Length: 328
• Identity: 105/328 - (32%)
• Similarity: 149/328 - (45%)
• Gaps: 46/328 - (14%)

  Fly   127 LTDDAIVHSVNSIHRLGWSARKYDQWWGRKYSEGLKLRLGTKEPTYRVKAMTRLK--------NP 183
            |..|..:..|.|..:.....|.:|    ...:||...||....|.....|:...:        |.
  Fly    23 LLSDEFIEVVRSKAKTWTVGRNFD----ASVTEGHIRRLMGVHPDAHKFALPDKREVLGDLYVNS 83

  Fly   184 TDGLPSSFNALDKWSS--YISEVPDQGWCGASWVLSTTSVASDRFAIQSKGKENVQLSAQNILSC 246
            .|.||..|::..:|.:  .|.|:.|||.||:.|........|||..|.|.||.|...||.:::||
  Fly    84 VDELPEEFDSRKQWPNCPTIGEIRDQGSCGSCWAFGAVEAMSDRVCIHSGGKVNFHFSADDLVSC 148

  Fly   247 TRR-QQGCEGGHLDAAWRYLHKKGVV-------DENCYPY----TQH-----RDTCKIRHNSRSL 294
            ... ..||.||...|||.|..:||:|       ::.|.||    .:|     |..|  .|..|:.
  Fly   149 CHTCGFGCNGGFPGAAWSYWTRKGIVSGGPYGSNQGCRPYEISPCEHHVNGTRPPC--AHGGRTP 211

  Fly   295 R-ANGCQKPVNVD--RDSLYTVGPAYSLNREA-DIMAEIFHSGPVQATMRVNRDFFAYSGGVYRE 355
            : ::.||....||  :|..:. ..:||:.|.. :|..||..:|||:....|..|...|..|||:.
  Fly   212 KCSHVCQSGYTVDYAKDKHFG-SKSYSVRRNVREIQEEIMTNGPVEGAFTVYEDLILYKDGVYQH 275

  Fly   356 TAANRKAPTGFHSVKLVGWGEEHNGEK---YWIAANSWGSWWGEHGYFRILRGSNECGIEEYVLA 417
            .....   .|.|:::::|||..  ||:   ||:..|||.:.||:||:||||||.:.||||..:.|
  Fly   276 EHGKE---LGGHAIRILGWGVW--GEEKIPYWLIGNSWNTDWGDHGFFRILRGQDHCGIESSISA 335

  Fly   418 SWP 420
            ..|
  Fly   336 GLP 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Swim	NP_611652.2	Somatomedin_B	41..83	CDD:279385
		VWC	91..>126	CDD:302663
		Peptidase_C1A_CathepsinB	188..417	CDD:239111	88/254 (35%)
CtsB1	NP_001259536.2	Propeptide_C1	24..64	CDD:285358	10/43 (23%)
		Peptidase_C1A_CathepsinB	88..336	CDD:239111	88/255 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452966
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR12411
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940