Protein Alignment Swim and Ctsk

DIOPT Version :10

• Sequence 1: NP_611652.2
• Gene: Swim / 37537
• FlyBaseID: FBgn0034709
• Length: 431
• Species: Drosophila melanogaster
• Sequence 2: NP_113748.1
• Gene: Ctsk / 29175
• RGDID: 61810
• Length: 329
• Species: Rattus norvegicus
• Alignment Length: 294
• Identity: 87/294 - (29%)
• Similarity: 139/294 - (47%)
• Gaps: 35/294 - (11%)

  Fly   138 SIHRLGWS--ARKYD---QWWGRKYSEGLKLRL-GTKEPTYRVKAMTRLKNPT-DG-LPSSFNAL 194
            |:|.|..|  |..|:   ...|...||.:..:: |.:.|..|..:...|..|. :| :|.|.:..
  Rat    58 SVHNLEASLGAHTYELAMNHLGDMTSEEVVQKMTGLRVPPSRSFSNDTLYTPEWEGRVPDSIDYR 122

  Fly   195 DKWSSYISEVPDQGWCGASWVLSTTSVASDRFAIQSKGKENVQLSAQNILSCTRRQQGCEGGHLD 259
            .|  .|::.|.:||.||:.|..|:......:  ::.|..:.:.||.||::.|.....||.||::.
  Rat   123 KK--GYVTPVKNQGQCGSCWAFSSAGALEGQ--LKKKTGKLLALSPQNLVDCVSENYGCGGGYMT 183

  Fly   260 AAWRYLHKKGVVD-ENCYPYTQHRDTCKIRHNSRSLRANGCQKPVNVDRDSLYTVGPAYSLNREA 323
            .|::|:.:.|.:| |:.|||....::|.....:::.:..|.::         ..||...:|.|
  Rat   184 TAFQYVQQNGGIDSEDAYPYVGQDESCMYNATAKAAKCRGYRE---------IPVGNEKALKR-- 237

  Fly   324 DIMAEIFHSGPVQATMRVN-RDFFAYSGGVYRETAANRKAPTGFHSVKLVGWGEEHNGEKYWIAA 387
                .:...|||..::..: ..|..||.|||.:...:|....  |:|.:||:|.: .|.||||..
  Rat   238 ----AVARVGPVSVSIDASLTSFQFYSRGVYYDENCDRDNVN--HAVLVVGYGTQ-KGNKYWIIK 295

  Fly   388 NSWGSWWGEHGYFRILRG-SNECGIEEYVLASWP 420
            ||||..||..||..:.|. :|.|||..  |||:|
  Rat   296 NSWGESWGNKGYVLLARNKNNACGITN--LASFP 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Swim	NP_611652.2	Somatomedin_B	41..84	CDD:460034
		Peptidase_C1A_CathepsinB	188..417	CDD:239111	68/231 (29%)
Ctsk	NP_113748.1	Inhibitor_I29	26..85	CDD:214853	8/26 (31%)
		Peptidase_C1	115..327	CDD:425470	71/235 (30%)