Protein Alignment Swim and Cts7

DIOPT Version :10

• Sequence 1: NP_611652.2
• Gene: Swim / 37537
• FlyBaseID: FBgn0034709
• Length: 431
• Species: Drosophila melanogaster
• Sequence 2: NP_001099569.1
• Gene: Cts7 / 290970
• RGDID: 1309226
• Length: 331
• Species: Rattus norvegicus
• Alignment Length: 298
• Identity: 83/298 - (27%)
• Similarity: 129/298 - (43%)
• Gaps: 44/298 - (14%)

  Fly   138 SIHRLGWSARKYDQWWGRKYSE--------GLKLRLGTKEPTYRVKAMTRLKNPTDGLPSSFNAL 194
            ::..:.|...:...|......|        |.::|:.|......::....::.....:|.:.:..
  Rat    55 NVKMIKWHTMQNGLWMNNFTIEMNEFGDMTGEEMRMMTDSSALTLRNGKHIQKRNVKIPKTLDWR 119

  Fly   195 DKWSSYISEVPDQGWCGASWVLS-TTSVASDRFAIQSKGKENVQLSAQNILSC--TRRQQGCEGG 256
            |  :..::.|..||.|||.|..| ..|:.|..|   .|..:.:.||.||::.|  |.....|.||
  Rat   120 D--TGCVAPVRSQGGCGACWAFSVAASIESQLF---KKTGKLIPLSVQNLIDCTVTYGNNDCSGG 179

  Fly   257 HLDAAWRYLHKKGVVD-ENCYPYTQHRDTCKIRHNSRSLRANGCQ-KPV-NVDRDSLYTVGPAYS 318
            ....|::|:...|.:: |..|||     ..|:||         |: :|. :|.:.:.:.|.|.
  Rat   180 KPYTAFQYVKNNGGLEAEATYPY-----EAKLRH---------CRYRPERSVVKIARFFVVPR-- 228

  Fly   319 LNREADIMAEIFHSGPVQATM-RVNRDFFAYSGGVYRETAANRKAPTGFHSVKLVGWG-EEHNGE 381
             |.|| :|..:...||:...: ..:..|..|.||:|.|....|  .|..|.:.|||:| |.|..|
  Rat   229 -NEEA-LMQALVTYGPIAVAIDGSHASFKRYRGGIYHEPKCRR--DTLDHGLLLVGYGYEGHESE 289

  Fly   382 --KYWIAANSWGSWWGEHGYFRILRGSNE-CGIEEYVL 416
              |||:..||.|..|||.||.::.|..|. |||..|.:
  Rat   290 NRKYWLLKNSHGEQWGERGYMKLPRDQNNYCGIASYAM 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Swim	NP_611652.2	Somatomedin_B	41..84	CDD:460034
		Peptidase_C1A_CathepsinB	188..417	CDD:239111	77/240 (32%)
Cts7	NP_001099569.1	Inhibitor_I29	29..87	CDD:214853	4/31 (13%)
		Nuclear localization signal. /evidence=ECO:0000250|UniProtKB:Q91ZF2	33..50
		Peptidase_C1A	113..329	CDD:239068	77/240 (32%)