Protein Alignment Swim and Tinag

DIOPT Version :10

• Sequence 1: NP_611652.2
• Gene: Swim / 37537
• FlyBaseID: FBgn0034709
• Length: 431
• Species: Drosophila melanogaster
• Sequence 2: NP_036163.3
• Gene: Tinag / 26944
• MGIID: 1349477
• Length: 475
• Species: Mus musculus
• Alignment Length: 435
• Identity: 173/435 - (39%)
• Similarity: 235/435 - (54%)
• Gaps: 44/435 - (10%)

  Fly    24 DHTL------KRD-FPGPYCARENTCCKDRHDGCSVPI--SNTLCYCDEFCDRDDSSDCCPDYRS 79
            :||:      ||. |.|.||.|.. ||:.|.|.|....  :|.|||||.||:| |:|||||||:|
Mouse    37 NHTIFEGSRHKRAIFQGEYCRRFG-CCEARDDTCVTQFYEANALCYCDSFCER-DTSDCCPDYKS 99

  Fly    80 FCIGE---------VDPIISCEHNGVYFSKYNTTWDNCNECRCLEGGSVQCDEDLCLTDDAIVHS 135
            ||..|         .|| ..|..:..::.:.:...:|||.|.| .|...:|.:.:||....::..
Mouse   100 FCHEEKEEPPFQQPSDP-EGCFRDSQHYEEGSVVKENCNSCTC-SGQQWKCSQHVCLVHPELIDH 162

  Fly   136 VNSIHRLGWSARKYDQWWGRKYSEGLKLRLGTKEPT---YRVKAMTRLKNPTDGLPSSFNALDKW 197
            :|. ...||:|:.|.|:||....||.|.||||..|:   ..:..||....|...||..|.|..||
Mouse   163 INK-GDYGWTAQNYSQFWGMTLEEGFKFRLGTLPPSPMLLSMNEMTASFPPRADLPEIFIASYKW 226

  Fly   198 SSYISEVPDQGWCGASWVLSTTSVASDRFAIQSKGKENVQLSAQNILS-CTRRQQGCEGGHLDAA 261
            ..:.....||..|.|||..||.|||:||.||||||:....||.||::| |.:.:.||..|.:|.|
Mouse   227 PGWTHGPLDQKNCAASWAFSTASVAADRIAIQSKGRYTANLSPQNLISCCAKNRHGCNSGSIDRA 291

  Fly   262 WRYLHKKGVVDENCYPYTQHRDT----CKI--RHNSRSLRANGCQKPVNVDRDS-LYTVGPAYSL 319
            |.:|.|:|:|...|||..:.::|    |.:  |.:.|..|......|.:.::.: :|...|.|.:
Mouse   292 WWFLRKRGLVSHACYPLFKDQNTTNNICAMASRSDGRGKRHATKPCPNSFEKSNRIYQCSPPYRV 356

  Fly   320 -NREADIMAEIFHSGPVQATMRVNRDFFAYSGGVYRETAANRKAPTGF-----HSVKLVGWGEEH 378
             :.|.:||.||..:|||||.|:|:.|||.|..|:||...:..:.|..:     |:|||.|||...
Mouse   357 SSNETEIMREIIQNGPVQAIMQVHEDFFYYKTGIYRHVVSTNEEPEKYKKLRTHAVKLTGWGTLR 421

  Fly   379 NG----EKYWIAANSWGSWWGEHGYFRILRGSNECGIEEYVLASW 419
            ..    ||:||||||||..|||:||||||||.||..||:.::|:|
Mouse   422 GARGKKEKFWIAANSWGKSWGENGYFRILRGVNESDIEKLIIAAW 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Swim	NP_611652.2	Somatomedin_B	41..84	CDD:460034	25/44 (57%)
		Peptidase_C1A_CathepsinB	188..417	CDD:239111	104/246 (42%)
Tinag	NP_036163.3	Somatomedin_B	60..105	CDD:470596	25/46 (54%)
		VWC	119..>166	CDD:450195	11/48 (23%)
		Peptidase_C1A_CathepsinB	217..465	CDD:239111	104/247 (42%)