Protein Alignment Swim and cpl-1

DIOPT Version :10

• Sequence 1: NP_611652.2
• Gene: Swim / 37537
• FlyBaseID: FBgn0034709
• Length: 431
• Species: Drosophila melanogaster
• Sequence 2: NP_001256718.1
• Gene: cpl-1 / 180111
• WormBaseID: WBGene00000776
• Length: 337
• Species: Caenorhabditis elegans
• Alignment Length: 301
• Identity: 92/301 - (30%)
• Similarity: 135/301 - (44%)
• Gaps: 36/301 - (11%)

  Fly   133 VHSVNSIHRLGWSARKYDQWWGRKYSEGLKLRLGTKEPTY-RVKAMTRLKNPTDGL-PSSFNALD 195
            :.:.|..||||   ||..: .|..:...|......|...| |:...:|:||.:..| |.:....|
 Worm    62 IENHNRDHRLG---RKTFE-MGLNHIADLPFSQYRKLNGYRRLFGDSRIKNSSSFLAPFNVQVPD 122

  Fly   196 K--W--SSYISEVPDQGWCGASWVLSTTSVASDRFAIQSKGKENVQLSAQNILSCTRR--QQGCE 254
            :  |  :..:::|.:||.||:.|..|.|.....:.|  .|..:.|.||.||::.|:.:  ..||.
 Worm   123 EVDWRDTHLVTDVKNQGMCGSCWAFSATGALEGQHA--RKLGQLVSLSEQNLVDCSTKYGNHGCN 185

  Fly   255 GGHLDAAWRYLH-KKGVVDENCYPYTQHRDTCKIRHNSRSLRANGCQKPVNVDRDSLYTVGPAYS 318
            ||.:|.|:.|:. ..||..|..|||           ..|.::.:..:|.|..| |..|...|.
 Worm   186 GGLMDQAFEYIRDNHGVDTEESYPY-----------KGRDMKCHFNKKTVGAD-DKGYVDTPE-- 236

  Fly   319 LNREADIMAEIFHSGPVQATMRV-NRDFFAYSGGVYRETAANRKAPTGFHSVKLVGWGEEHNGEK 382
             ..|..:...:...||:...:.. :|.|..|..|||.:...:.:...  |.|.|||:|.:.....
 Worm   237 -GDEEQLKIAVATQGPISIAIDAGHRSFQLYKKGVYYDEECSSEELD--HGVLLVGYGTDPEHGD 298

  Fly   383 YWIAANSWGSWWGEHGYFRILRG-SNECGIEEYVLASWPYV 422
            |||..||||:.|||.||.||.|. :|.||:.  ..||:|.|
 Worm   299 YWIVKNSWGAGWGEKGYIRIARNRNNHCGVA--TKASYPLV 337

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Swim	NP_611652.2	Somatomedin_B	41..84	CDD:460034
		Peptidase_C1A_CathepsinB	188..417	CDD:239111	72/237 (30%)
cpl-1	NP_001256718.1	Inhibitor_I29	32..91	CDD:462410	9/32 (28%)
		Peptidase_C1	120..336	CDD:425470	73/236 (31%)