Protein Alignment Swim and cpr-5

DIOPT Version :10

• Sequence 1: NP_611652.2
• Gene: Swim / 37537
• FlyBaseID: FBgn0034709
• Length: 431
• Species: Drosophila melanogaster
• Sequence 2: NP_503383.1
• Gene: cpr-5 / 178612
• WormBaseID: WBGene00000785
• Length: 344
• Species: Caenorhabditis elegans
• Alignment Length: 341
• Identity: 109/341 - (31%)
• Similarity: 156/341 - (45%)
• Gaps: 76/341 - (22%)

  Fly   127 LTDDAIVHSVNSIHRLGWSARKYDQWWGRKYSEGLKLRLGTKEPTYRVKAMTRLKNP-------T 184
            ||..|::..|||..:| |:|       |.:.....|:   ||: ...||.:...|:.       :
 Worm    27 LTGQALIDYVNSAQKL-WTA-------GHQVIPKEKI---TKK-LMDVKYLVPHKDEDIVATEVS 79

  Fly   185 DGLPSSFNALDKWSS--YISEVPDQGWCGASWVLSTTSVASDRFAIQSKGKENVQLSAQNILSCT 247
            |.:|..|:|.|:|.:  .|:.:.||..||:.|..:.....|||..|.|.|..|..||::::|||.
 Worm    80 DAIPDHFDARDQWPNCMSINNIRDQSDCGSCWAFAAAEAISDRTCIASNGAVNTLLSSEDLLSCC 144

  Fly   248 RRQ----QGCEGGHLDAAWRYLHKKGVV-------DENCYPYT---------------------- 279
            ...    .|||||:...||::..|.|:|       ...|.||:
 Worm   145 TGMFSCGNGCEGGYPIQAWKWWVKHGLVTGGSYETQFGCKPYSIAPCGETVNGVKWPACPEDTEP 209

  Fly   280 --QHRDTCKIRHNSRSLRANGCQKPVNVDR---DSLYTVGPAYSLNREADIMAEIFHSGPVQATM 339
              :..|:|..::|..:        |...|:   .:.|.||     .:...|..||..:||::...
 Worm   210 TPKCVDSCTSKNNYAT--------PYLQDKHFGSTAYAVG-----KKVEQIQTEILTNGPIEVAF 261

  Fly   340 RVNRDFFAYSGGVYRETAANRKAPTGFHSVKLVGWGEEHNGEKYWIAANSWGSWWGEHGYFRILR 404
            .|..||:.|:.|||..||.   |..|.|:||::|||.: ||..||:.||||...|||.|||||:|
 Worm   262 TVYEDFYQYTTGVYVHTAG---ASLGGHAVKILGWGVD-NGTPYWLVANSWNVAWGEKGYFRIIR 322

  Fly   405 GSNECGIEEYVLASWP 420
            |.||||||...:|..|
 Worm   323 GLNECGIEHSAVAGIP 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Swim	NP_611652.2	Somatomedin_B	41..84	CDD:460034
		Peptidase_C1A_CathepsinB	188..417	CDD:239111	90/268 (34%)
cpr-5	NP_503383.1	Peptidase_C1A_CathepsinB	83..336	CDD:239111	90/269 (33%)