Protein Alignment Swim and Ctss

DIOPT Version :10

• Sequence 1: NP_611652.2
• Gene: Swim / 37537
• FlyBaseID: FBgn0034709
• Length: 431
• Species: Drosophila melanogaster
• Sequence 2: NP_001254624.2
• Gene: Ctss / 13040
• MGIID: 107341
• Length: 341
• Species: Mus musculus
• Alignment Length: 302
• Identity: 87/302 - (28%)
• Similarity: 142/302 - (47%)
• Gaps: 48/302 - (15%)

  Fly   139 IHRLGWSARKYDQW-----WGRKYSEGLKLRLGT-KEPTYRVKAMTRLKNPTDGLPSSFNALDKW 197
            ||.|.:|...:...     .|...:|.:..|:|. :.|....|.:|........||.:.:..:|
Mouse    70 IHNLEYSMGMHTYQVGMNDMGDMTNEEILCRMGALRIPRQSPKTVTFRSYSNRTLPDTVDWREK- 133

  Fly   198 SSYISEVPDQGWCGASWVLSTTSVASDRFAIQSKGKENVQLSAQNILSCTRRQ----QGCEGGHL 258
             ..::||..||.|||.|..|.......:..::: || .:.|||||::.|:..:    :||.||::
Mouse   134 -GCVTEVKYQGSCGACWAFSAVGALEGQLKLKT-GK-LISLSAQNLVDCSNEEKYGNKGCGGGYM 195

  Fly   259 DAAWRYLHKKGVVDENC-YPYTQHRDTCKIRHNSRSLRANGCQKPVNV---DRDSLYTVGPAYSL 319
            ..|::|:...|.::.:. |||....:.|  .:||:: ||..|.:.:.:   |.|:|
Mouse   196 TEAFQYIIDNGGIEADASYPYKATDEKC--HYNSKN-RAATCSRYIQLPFGDEDAL--------- 248

  Fly   320 NREADIMAEIFHSGPVQATMRVNR-DFFAYSGGVYRETAANRKAPTG--FHSVKLVGWGEEHNGE 381
             :||     :...|||...:..:. .||.|..|||.:.:.     ||  .|.|.:||:| ..:|:
Mouse   249 -KEA-----VATKGPVSVGIDASHSSFFFYKSGVYDDPSC-----TGNVNHGVLVVGYG-TLDGK 301

  Fly   382 KYWIAANSWGSWWGEHGYFRILRGS-NECGIEEYVLASWPYV 422
            .||:..||||..:|:.||.|:.|.: |.|||..|  .|:|.:
Mouse   302 DYWLVKNSWGLNFGDQGYIRMARNNKNHCGIASY--CSYPEI 341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Swim	NP_611652.2	Somatomedin_B	41..84	CDD:460034
		Peptidase_C1A_CathepsinB	188..417	CDD:239111	73/240 (30%)
Ctss	NP_001254624.2	Inhibitor_I29	37..96	CDD:214853	5/25 (20%)
		Peptidase_C1	124..339	CDD:425470	75/244 (31%)