Protein Alignment Swim and Ctsb

DIOPT Version :10

• Sequence 1: NP_611652.2
• Gene: Swim / 37537
• FlyBaseID: FBgn0034709
• Length: 431
• Species: Drosophila melanogaster
• Sequence 2: NP_031824.1
• Gene: Ctsb / 13030
• MGIID: 88561
• Length: 339
• Species: Mus musculus
• Alignment Length: 332
• Identity: 111/332 - (33%)
• Similarity: 164/332 - (49%)
• Gaps: 53/332 - (15%)

  Fly   127 LTDDAIVHSVNSIHRLGWSARKYDQWWGRKY----SEGLKLRLGTKEPTYRVKAMTRLKNPTDGL 187
            |:|| :::.:|. ....|.|       ||.:    ...||...||.....::..........| |
Mouse    26 LSDD-LINYINK-QNTTWQA-------GRNFYNVDISYLKKLCGTVLGGPKLPGRVAFGEDID-L 80

  Fly   188 PSSFNALDKWSS--YISEVPDQGWCGASWVLSTTSVASDRFAIQSKGKENVQLSAQNILSCTRRQ 250
            |.:|:|.::||:  .|.::.|||.||:.|........|||..|.:.|:.||::||:::|:|...|
Mouse    81 PETFDAREQWSNCPTIGQIRDQGSCGSCWAFGAVEAISDRTCIHTNGRVNVEVSAEDLLTCCGIQ 145

  Fly   251 --QGCEGGHLDAAWRYLHKKGVVD-------ENCYPYT----QHR------------DTCKIRHN 290
              .||.||:...||.:..|||:|.       ..|.|||    :|.            ||.:.
Mouse   146 CGDGCNGGYPSGAWSFWTKKGLVSGGVYNSHVGCLPYTIPPCEHHVNGSRPPCTGEGDTPRC--- 207

  Fly   291 SRSLRANGCQKPVNVDRDSLYTVGPAYSL-NREADIMAEIFHSGPVQATMRVNRDFFAYSGGVYR 354
            ::|..| |.......|:...||   :||: |...:|||||:.:|||:....|..||..|..|||:
Mouse   208 NKSCEA-GYSPSYKEDKHFGYT---SYSVSNSVKEIMAEIYKNGPVEGAFTVFSDFLTYKSGVYK 268

  Fly   355 ETAANRKAPTGFHSVKLVGWGEEHNGEKYWIAANSWGSWWGEHGYFRILRGSNECGIEEYVLASW 419
            ..|.:.   .|.|:::::|||.| ||..||:|||||...||::|:|:||||.|.||||..::|..
Mouse   269 HEAGDM---MGGHAIRILGWGVE-NGVPYWLAANSWNLDWGDNGFFKILRGENHCGIESEIVAGI 329

  Fly   420 PYVYSYY 426
            |....|:
Mouse   330 PRTDQYW 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Swim	NP_611652.2	Somatomedin_B	41..84	CDD:460034
		Peptidase_C1A_CathepsinB	188..417	CDD:239111	94/256 (37%)
Ctsb	NP_031824.1	Propeptide_C1	26..65	CDD:462365	12/47 (26%)
		Peptidase_C1A_CathepsinB	81..328	CDD:239111	94/257 (37%)