DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11275 and SPOPL

DIOPT Version :9

Sequence 1:	NP_611649.1	Gene:	CG11275 / 37534	FlyBaseID:	FBgn0034706	Length:	417	Species:	Drosophila melanogaster
Sequence 2:	NP_001001664.1	Gene:	SPOPL / 339745	HGNCID:	27934	Length:	392	Species:	Homo sapiens

Alignment Length:	222	Identity:	59/222 - (26%)
Similarity:	95/222 - (42%)	Gaps:	44/222 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 LGRRYGQLLRGAKYTDCVFHVCEEQVKCHKLILSSASPVFEAMFFGPMQNNEPEPEIEIHDISSA 82
            |....|.|....::|||.|.|..::.|.||.:|::.||||.|||...|:.:: :..:||:|:...
Human   186 LAEDLGNLWENTRFTDCSFFVRGQEFKAHKSVLAARSPVFNAMFEHEMEESK-KNRVEINDLDPE 249

  Fly    83 IFKVLVEYIYTGVVDYNGLELVACIELYYAAEKYLLEELIADTLMVITRKLRFANILPALELSVC 147
            :||.::.:||||...  .|:.:| ..|..||:||.||.|.......:...|...|:...|.|:..
Human   250 VFKEMMRFIYTGRAP--NLDKMA-DNLLAAADKYALERLKVMCEEALCSNLSVENVADTLVLADL 311

  Fly   148 MGLDGLLEVCMTFFMRCCV------------NNGQ---------YMSHLKEHYVHVSKECVKAII 191
            ...:.|....:.|..||.|            |:.|         :.|.::.| .|:..|..:|:.
Human   312 HSAEQLKAQAIDFINRCSVLRQLGCKDGKNWNSNQATDIMETSGWKSMIQSH-PHLVAEAFRALA 375

  Fly   192 AACKEPHKLLIWYVYEWTRQECEQLGL 218
            :|                  :|.|.|:
Human   376 SA------------------QCPQFGI 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11275	NP_611649.1	BTB	22..122	CDD:279045	37/99 (37%)
CG11275	NP_611649.1	BTB	33..122	CDD:197585	34/88 (39%)
SPOPL	NP_001001664.1	MATH	28..166	CDD:351761
		BTB_POZ_SPOPL	179..301	CDD:349652	40/118 (34%)
		BACK_SPOPL	297..392	CDD:350594	20/107 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24413
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X131
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.010