Protein Alignment Fbxo42 and hcfc1a

DIOPT Version :10

• Sequence 1: NP_611647.1
• Gene: Fbxo42 / 37532
• FlyBaseID: FBgn0034704
• Length: 667
• Species: Drosophila melanogaster
• Sequence 2: NP_001038529.2
• Gene: hcfc1a / 564853
• ZFINID: ZDB-GENE-030912-10
• Length: 1802
• Species: Danio rerio
• Alignment Length: 455
• Identity: 101/455 - (22%)
• Similarity: 160/455 - (35%)
• Gaps: 119/455 - (26%)

  Fly   103 RFAHSAVRQDNSMYVFGG--GSSSDTT------FNDLWRFDL----THMRWARPVATGTYPSPKG 155
            |..||.....|..|:|||  ..|.|..      .|||:..:|    :...|..||..|..|.|:.
Zfish   136 RLGHSFSLVGNKCYLFGGLANDSEDPKNNIPRYLNDLYTLELRPGSSVAGWDVPVTYGVLPPPRE 200

  Fly   156 SASMVAW------RNQLILFGGWRYPSLHPPYQPWCLFDELHYYDLGKNRWLLRS-SLSSPPPMA 213
            |.:.|.:      :::|:::||          ...|...:|...|:....|...: |.::|.|.:
Zfish   201 SHTAVIYTEKVTKKSRLVIYGG----------MSGCRLGDLWTLDIDTLTWNKPAISGAAPLPRS 255

  Fly   214 GHSATVHGDRMVVFGGY--QIKDDFNVNSND-TW-------VLDLPEQRWWQPLF--VGNTRPSP 266
            .||||...::|.||||:  .:.||..|.::: .|       .|:|....|...|.  :.:..|..
Zfish   256 LHSATTITNKMYVFGGWVPLVMDDVKVATHEKEWKCTNTLACLNLDTLAWETVLMDTLEDNIPRA 320

  Fly   267 RYGQIQVELGRNHLLIVGGCGGANRVYT------DAWLLDMTR-----------------DVWSW 308
            |.|...|.: .|.|.|..|..|..:.:.      |.|.|:..|                 :| ||
Zfish   321 RAGHCAVAI-NNRLYIWSGRDGYRKAWNNQVCCKDLWYLETERPNPPSRVQLVRANTNSLEV-SW 383

  Fly   309 KSIAVRNKRFGAVHMWCNPGCKVNNYLVVVGPSPNMPQDFQMMKQSRVPVVGGRGPPPPNP---- 369
            .:::..:.....:..:..|.       .....||.:         :..|.:.|..|..|.|
Zfish   384 GAVSTADTYLLQLQKYDIPA-------ATAATSPAL---------NAAPSLPGNSPKSPAPAAAA 432

  Fly   370 --LQNVPPRGY-RIP------------VPDRRLGGGGLGGPGQNRGGNIRPGVGGA------AAA 413
              .|::|..|. .:|            .|...|......||...:....:.|.|.:      |:.
Zfish   433 PSAQSLPHSGITSVPQAASPTASVLPGTPASPLAASMARGPAILKVAAPQSGTGASIVTVRQASQ 497

  Fly   414 LGPQEQYLANRRAILNQHMQQAQQFLHNSNVNNNNNNYQPRSGRLSDLHAPPAAAAAAS--PPSP 476
            :|.....:|:..|  ...|....|....:.:.:        |.::|.:.|..|||||..  ||||
Zfish   498 VGKSPVTVASLPA--GVRMVVPSQTAQGTPIGS--------SPQMSGMAALAAAAAATQKIPPSP 552

  Fly   477  476
            Zfish   553  552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fbxo42	NP_611647.1	F-box_FBXO42	24..61	CDD:438882
		NanM	<101..307	CDD:442289	63/257 (25%)
		KELCH repeat	103..148	CDD:276965	17/56 (30%)
		KELCH repeat	154..209	CDD:276965	10/61 (16%)
		KELCH repeat	212..257	CDD:276965	16/54 (30%)
		KELCH repeat	267..314	CDD:276965	15/69 (22%)
hcfc1a	NP_001038529.2	None