Protein Alignment Fbxo42 and fbxo42

DIOPT Version :10

• Sequence 1: NP_611647.1
• Gene: Fbxo42 / 37532
• FlyBaseID: FBgn0034704
• Length: 667
• Species: Drosophila melanogaster
• Sequence 2: NP_001428920.1
• Gene: fbxo42 / 335459
• ZFINID: ZDB-GENE-030131-7399
• Length: 629
• Species: Danio rerio
• Alignment Length: 709
• Identity: 221/709 - (31%)
• Similarity: 324/709 - (45%)
• Gaps: 138/709 - (19%)

  Fly     9 DGENDNC---------GATLAAV-NLNVLPDEILEFIFTYLPPYGDLEHCSLVCKRWHAIVKNLV 63
            ||| |:|         ||.|.|. ::..||:|:||:|.::|.||.:.:..:||||:|:.::|.:.
Zfish     6 DGE-DSCAVAMELEEGGAELKAEHSMAELPEEVLEYILSFLSPYQEHKTAALVCKQWYRLIKGVA 69

  Fly    64 RRSRHNLEKGLIDFRLRWEVFSQQTVNGGAGALLSFIAGRFAHSAVRQDN--SMYVFGG--GSSS 124
            .:..|...:.:.:..::||  |:.....|..     |..||:|||...|:  |||||||  .||.
Zfish    70 HQCYHGFLRAIQEGNIQWE--SRTYPYPGTP-----ITQRFSHSACYYDSNQSMYVFGGCTQSSC 127

  Fly   125 DTTFNDLWRFDLTHMRWARPVATGTYPSPKGSASMVAWRNQLILFGGWRYPSLHPPYQPWCLFDE 189
            :..||||||.||....|.||:|:|:|||||..|::|.:.:.|:|||||..||.:|.:||...|||
Zfish   128 NAAFNDLWRLDLNSKEWIRPLASGSYPSPKAGATLVMYGDLLVLFGGWTRPSPYPLHQPERFFDE 192

  Fly   190 LHYYDLGKNRWLLRSSLSSPPPMAGHSATVHGDRMVVFGG----YQIKDDFNVNSNDTWVLDLPE 250
            :|.|...||.|....:...||||||||::|....||||||    .|:       ||:.|||||.:
Zfish   193 IHTYSPSKNWWNCIVTTHGPPPMAGHSSSVIRSTMVVFGGSLGARQM-------SNEVWVLDLEQ 250

  Fly   251 QRWWQPLFVGNTRPSPRYGQIQVELGRNHLLIVGGCGGANRVYTDAWLLDMTRDVWSWKSIAVRN 315
            ..|.:|...|.: |.||.||.|:.:....|||:|||||.|.:..|||||.|:...|:|:.:.|.|
Zfish   251 WTWSKPTISGPS-PHPRGGQSQIVMDEETLLILGGCGGPNALLKDAWLLHMSDPCWTWQQLRVEN 314

  Fly   316 KRFGAVHMWCNPGCKVNNYLVVVGPSPNMPQDFQMMKQSRVPVVGGRGP------PPPNPLQNVP 374
            :..||..:||:|.|||...:||...:|:                 ||.|      ..|:|:.:.|
Zfish   315 EDHGAPELWCHPACKVGQCVVVFSQAPS-----------------GRAPLSPSLNSRPSPISSTP 362

  Fly   375 ------PRGYRIPVPDRRLGGGGLGG-----PGQN-RGGNIRPGVGGAAA-----ALGPQEQYLA 422
                  |...|...|.|....|.:.|     |..| |.|.:||.....|:     :.||....|.
Zfish   363 APLGPDPPSLRSQSPVRSGAAGAVLGAVEEAPCVNGRWGTLRPRASARASSSSSPSRGPDSPPLL 427

  Fly   423 N------RRAILNQHMQQAQQFLHNSNVNNNNNNYQPRSGRLSDLHAPPAAAAAASPPSPPVRPN 481
            |      |.:.:.|....|:               .|....||...:||:|....:||..|..|.
Zfish   428 NGASPSPRTSPVQQASPPAR---------------PPGPADLSWDGSPPSANGLHTPPGSPRTPP 477

  Fly   482 APPSPADGDVDAAQRLQRNL-ALRCRDNEPRLPKRFDELYEDPFRMAAFNVPTRSRSASRDHNER 545
            ...|||        .|:|.| |::...:.|..|         |......:.|:.:..|.......
Zfish   478 GAVSPA--------ALRRGLEAVKASSSLPSPP---------PAPQPGPSAPSGTPPAPASPPPI 525

  Fly   546 IRRMEEKMNAIRNSRRSAPAAAQVEPQPLRAPSP--KRLRCNVQSLFVCDISGILDSSEPALEWV 608
            .||:                 ....||.|....|  :.|.|....:::.|:|..  .::..:.|.
Zfish   526 ARRL-----------------GHHPPQSLNVGKPLYQALSCKPMQMYLLDVSRA--RTQGVVAWR 571

  Fly   609 EYKNFG---VLKGAPDRLILSSLIAGNGELILFGGVHKETLTDITHHVSNSIHFLSVPR 664
            .|.:.|   .:.|.|: ..|.:::.|.||||:|||:..:......:..:|:::|:...|
Zfish   572 VYGSGGAPSAVTGPPE-TSLHTVVQGRGELIIFGGLMDKKQNVKYYPKTNALYFVRAKR 629

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fbxo42	NP_611647.1	F-box_FBXO42	24..61	CDD:438882	14/36 (39%)
		NanM	<101..307	CDD:442289	101/213 (47%)
		KELCH repeat	103..148	CDD:276965	27/48 (56%)
		KELCH repeat	154..209	CDD:276965	22/54 (41%)
		KELCH repeat	212..257	CDD:276965	21/48 (44%)
		KELCH repeat	267..314	CDD:276965	21/46 (46%)
fbxo42	NP_001428920.1	None