DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3045 and Pus3

DIOPT Version :9

Sequence 1:	NP_611646.1	Gene:	CG3045 / 37531	FlyBaseID:	FBgn0034703	Length:	499	Species:	Drosophila melanogaster
Sequence 2:	NP_001101604.1	Gene:	Pus3 / 315554	RGDID:	1310757	Length:	479	Species:	Rattus norvegicus

Alignment Length:	471	Identity:	188/471 - (39%)
Similarity:	262/471 - (55%)	Gaps:	68/471 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 RNLLQKKLSEKDKHDKEYSGLIGNEAEG-KVSQVAKTSSKVQKI-RKFDWSSAHKRHVLLKITYF 108
            ||.::|.||...:.::|...|...:|.. |.:.|.:.|....|. |.||:|:..:|||.|||.|.
  Rat     7 RNQIEKLLSRVKELEQEVERLKKEQANNIKDTSVRENSLGCGKAKRAFDFSAHGRRHVALKIAYL 71

  Fly   109 GWDYQGFACQEDSNDTIESNLFRALARTCLIESRATSNYHRCGRTDKEVSAFCQVISIDLRSKHP 173
            ||.|||||.||::::|||..||.||.:|.|:|||.||||||||||||.||||.||||:||||:.|
  Rat    72 GWGYQGFASQENTSNTIEEKLFEALIKTRLVESRQTSNYHRCGRTDKGVSAFGQVISLDLRSQFP 136

  Fly   174 -----PESQLDPTA--LSSEIDYCGLLNRVLPKNIQCVAWMPLRSPVYSARFDCVSRTYRYYFPK 231
                 .:|.|...|  ::.||.|..:||||||.:|:.:||.| ..|.:||||.|:.|||||:||.
  Rat   137 RSRDSEDSNLKDGADDIAKEIRYAHILNRVLPADIRVLAWAP-AEPSFSARFSCLERTYRYFFPC 200

  Fly   232 GDLDIAAMRKACDLLVRHADFRNFCKMDVHNGVTNYMRNLQSARVEACDQT---NHTNSGYDMYY 293
            .|||||.|..|....|...||||.|||||.|||||:.|.:.||:|:...|:   ......:.:..
  Rat   201 ADLDIATMNYAAQKYVGTHDFRNLCKMDVANGVTNFQRTILSAQVQTVAQSPGEEGRQGPFQLCQ 265

  Fly   294 LEIQANAFLWHQIRCIMAVLLLVGQKKENPGVISDLLDVESNPCKPQYTPAIGLPLNLFRCDFRD 358
            .|:...|||:||:||:||:|.|:||..|.|.:|.:||::|.||.||||:.|:..||.|:.|.|.:
  Rat   266 FEVIGQAFLYHQVRCMMAILFLIGQGMEKPEIIDELLNIEKNPQKPQYSMAVEFPLVLYDCKFEN 330

  Fly   359 HTTRSVNHPSSGDADEEAMDTAADESNDLNAPEHLERDLTAWIYNEENLQKLIENTQCEWTQFSV 423
                                                   |.|||:.|..:..:.:.|..|...:|
  Rat   331 ---------------------------------------TKWIYDHEVHEFNVTHLQQLWANHAV 356

  Fly   424 KSTMIRNVLQQLENLFE--------------ENFKPKEKVLAQVILLQDSVNPRQYQPLLERKRC 474
            |:.|:.::||.|:::..              .|.:|  .|:.......:.|..|.|:||:.|.:|
  Rat   357 KTHMLYSMLQGLDSVMVTCAAGTKTGEATEWRNIRP--SVIKHTSAFVEGVRMRTYKPLMARPKC 419

  Fly   475 ESLENRIEHFVKKQRL 490
            :.||:||:|||::.|:
  Rat   420 QGLESRIQHFVRRGRI 435

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3045	NP_611646.1	TruA	101..376	CDD:223179	139/284 (49%)
CG3045	NP_611646.1	PseudoU_synth_ScPus3	103..356	CDD:211336	137/262 (52%)
Pus3	NP_001101604.1	TruA	64..334	CDD:223179	140/309 (45%)
Pus3	NP_001101604.1	PseudoU_synth_ScPus3	66..328	CDD:211336	137/262 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166341825
Domainoid	1	1.000	181	1.000	Domainoid score	I3398
eggNOG	1	0.900	-	-		E1_COG0101
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11339
Inparanoid	1	1.050	316	1.000	Inparanoid score	I2480
OMA	1	1.010	-	-		QHG54236
OrthoDB	1	1.010	-	-		D1093493at2759
OrthoFinder	1	1.000	-	-		FOG0004137
OrthoInspector	1	1.000	-	-		oto97731
orthoMCL	1	0.900	-	-		OOG6_100424
Panther	1	1.100	-	-	LDO	PTHR11142
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2401
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770