Protein Alignment CG30280 and TNR

DIOPT Version :10

• Sequence 1: NP_611641.6
• Gene: CG30280 / 37522
• FlyBaseID: FBgn0050280
• Length: 288
• Species: Drosophila melanogaster
• Sequence 2: NP_003276.3
• Gene: TNR / 7143
• HGNCID: 11953
• Length: 1358
• Species: Homo sapiens
• Alignment Length: 256
• Identity: 96/256 - (37%)
• Similarity: 139/256 - (54%)
• Gaps: 17/256 - (6%)

  Fly    31 LEAIYEQAENA--LSTLQESLLQLETNGTLNTSPDVI-YPTSC---LTSGDLENGLHTLKVPG-L 88
            ||.:.|..:..  |...|::.....|:....|...|. :|..|   |.:||..:|::.:.:.| |
Human  1096 LEGLLENTDYTVLLQAAQDTTWSSITSTAFTTGGRVFPHPQDCAQHLMNGDTLSGVYPIFLNGEL 1160

  Fly    89 S-PFQVYCENQLAGPGWIVIQKRFSGNLSFFRNWKEYKNGFGNLMDEYFLGLEKIRALTALEPHE 152
            | ..||||:....|.||||.|:|.:|...|||.|.:|:.||||:.||::|||:.|..:|:...:|
Human  1161 SQKLQVYCDMTTDGGGWIVFQRRQNGQTDFFRKWADYRVGFGNVEDEFWLGLDNIHRITSQGRYE 1225

  Fly   153 LYVHLEDFDDTIKHAKFDEFAIGNEDDDYAMNTLGKYSGTAGDSLRSHRKMKFSTYDRDNDHEFN 217
            |.|.:.|..:. ..|.:|.|::.:..:.|.:. :|.|:|||||||..|:...|||.|||||....
Human  1226 LRVDMRDGQEA-AFASYDRFSVEDSRNLYKLR-IGSYNGTAGDSLSYHQGRPFSTEDRDNDVAVT 1288

  Fly   218 KNCAFYYLGGWWYNACLDSNLNGQYMPGGKYEESLFARGMCWRSWRGHNYGYRVTQMMIRP 278
             |||..|.|.|||..|..:|||      |||.||..::|:.|..|:||.:.....:|.:||
Human  1289 -NCAMSYKGAWWYKNCHRTNLN------GKYGESRHSQGINWYHWKGHEFSIPFVEMKMRP 1342

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30280	NP_611641.6	FReD	65..279	CDD:238040	88/220 (40%)
TNR	NP_003276.3	EGF_Tenascin	203..231	CDD:376143
		C_rich_MXAN6577	207..312	CDD:469225
		EGF_Tenascin	235..261	CDD:480934
		fn3	328..398	CDD:394996
		fn3	416..496	CDD:394996
		fn3	507..583	CDD:394996
		FN3	<566..919	CDD:442628
		fn3	954..1026	CDD:394996
		FN3	1042..1127	CDD:238020	6/30 (20%)
		FReD	1133..1342	CDD:238040	86/217 (40%)