DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30280 and Angptl6

DIOPT Version :9

Sequence 1:	NP_611641.6	Gene:	CG30280 / 37522	FlyBaseID:	FBgn0050280	Length:	288	Species:	Drosophila melanogaster
Sequence 2:	XP_011240901.1	Gene:	Angptl6 / 70726	MGIID:	1917976	Length:	474	Species:	Mus musculus

Alignment Length:	242	Identity:	95/242 - (39%)
Similarity:	134/242 - (55%)	Gaps:	14/242 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 QESLLQLETNGTLNTSPDVIYPT-------SCLT---SGDLENGLHTLKVPGLSPFQVYCENQLA 100
            ::||.|.....:|..:..:..||       .|..   :|..::|::.|:: |.....|:||.|..
Mouse   233 EQSLRQQGPPSSLLPTGHLAVPTRPVGPWRDCAEAHGAGHWQSGVYDLRL-GRRVVAVWCEQQQE 296

  Fly   101 GPGWIVIQKRFSGNLSFFRNWKEYKNGFGNLMDEYFLGLEKIRALTALEPHELYVHLEDFDDTIK 165
            |.||.|||:|..|:::||.||:.||.|||....||:||||.:..:|:...|||.:.|||:.....
Mouse   297 GGGWTVIQRRQDGSVNFFTNWQHYKAGFGRPEGEYWLGLEPVHQVTSRGDHELLILLEDWGGRAA 361

  Fly   166 HAKFDEFAIGNEDDDYAMNTLGKYSGTAGDSLRSHRKMKFSTYDRDNDHEFNKNCAFYYLGGWWY 230
            .|.:|.|::..|.|.|.:. ||:|.|.|||||..|....|||.|||.| .::.|||.|:.|||||
Mouse   362 RAHYDSFSLEPESDHYRLR-LGQYHGDAGDSLSWHNDKPFSTVDRDRD-SYSGNCALYHRGGWWY 424

  Fly   231 NACLDSNLNGQYMPGGKYEESLFARGMCWRSWRGHNYGYRVTQMMIR 277
            :||..|||||.:..||.| .|.:..|:.|..:||..|..:...|:.|
Mouse   425 HACAHSNLNGVWYHGGHY-RSRYQDGVYWAEFRGGAYSLKKAVMLTR 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30280	NP_611641.6	FReD	65..279	CDD:238040	91/223 (41%)
Angptl6	XP_011240901.1	PRK09039	57..>154	CDD:181619
		AMH_N	<116..197	CDD:368070
		FReD	259..470	CDD:238040	88/214 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	187	1.000	Domainoid score	I3330
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910