DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30280 and angptl6

DIOPT Version :9

Sequence 1:	NP_611641.6	Gene:	CG30280 / 37522	FlyBaseID:	FBgn0050280	Length:	288	Species:	Drosophila melanogaster
Sequence 2:	NP_001014821.1	Gene:	angptl6 / 561927	ZFINID:	ZDB-GENE-030131-9735	Length:	489	Species:	Danio rerio

Alignment Length:	278	Identity:	100/278 - (35%)
Similarity:	153/278 - (55%)	Gaps:	22/278 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 SVMIFCHAETLNLFGNLEAIYEQAENALSTLQESLLQL--ETNGTLNTSPDVIYPTS-------- 69
            ||::..:.|..::..:..|.:.||:     .::.||:.  ::.|....:|.:.:|::
Zfish   219 SVLVNINTEPKDVQRDQSAPFHQAQ-----ARQELLETFDDSPGPPTETPFISFPSTKSPGPWHD 278

  Fly    70 C---LTSGDLENGLHTLKVPGLSP-FQVYCENQLAGPGWIVIQKRFSGNLSFFRNWKEYKNGFGN 130
            |   |.||:..:|::.|:....:. .|.:|:...|..||.|||:|..|:::|||.|.:||.||||
Zfish   279 CHNVLESGEKTSGIYLLRPRNTNRLLQAWCDQSRAQGGWTVIQRRQDGSVNFFRTWDQYKQGFGN 343

  Fly   131 LMDEYFLGLEKIRALTALEPHELYVHLEDFDDTIKHAKFDEFAIGNEDDDYAMNTLGKYSGTAGD 195
            |..||:||||.:..||:...::|.|.:||:.....:|::|.|.:..|.|.|.:. ||.|.|||||
Zfish   344 LDGEYWLGLEHLYWLTSQATYKLRVAMEDWQGRQVYAEYDSFRVEPESDWYRLR-LGSYQGTAGD 407

  Fly   196 SLRSHRKMKFSTYDRDNDHEFNKNCAFYYLGGWWYNACLDSNLNGQYMPGGKYEESLFARGMCWR 260
            ||..|....|:|.|||.| .:..|||.|..|||||:.|..|||||.:..||.| .|.:..|:.|.
Zfish   408 SLSWHNNKAFTTLDRDKD-AYTGNCAHYQKGGWWYHMCAHSNLNGVWYRGGHY-RSRYQDGVYWA 470

  Fly   261 SWRGHNYGYRVTQMMIRP 278
            .:.|.:|..:...|||:|
Zfish   471 EFHGGSYSLKKVAMMIKP 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30280	NP_611641.6	FReD	65..279	CDD:238040	90/226 (40%)
angptl6	NP_001014821.1	DUF1640	<46..150	CDD:285090
		DUF4349	<126..230	CDD:305044	3/10 (30%)
		FReD	274..488	CDD:238040	88/216 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	171	1.000	Inparanoid score	I4088
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000029
OrthoInspector	1	1.000	-	-		mtm6515
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3359
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.990