DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30280 and MFAP4

DIOPT Version :9

Sequence 1:	NP_611641.6	Gene:	CG30280 / 37522	FlyBaseID:	FBgn0050280	Length:	288	Species:	Drosophila melanogaster
Sequence 2:	NP_001185624.1	Gene:	MFAP4 / 4239	HGNCID:	7035	Length:	279	Species:	Homo sapiens

Alignment Length:	266	Identity:	97/266 - (36%)
Similarity:	138/266 - (51%)	Gaps:	31/266 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 QAENALSTLQESLLQLETNGTLNTSP----------DVI------YPTSC---LTSGDLENGLHT 82
            :|:..|  |:.:||.|.....|:|.|          |.:      .|..|   ...|...:|::.
Human    18 KAQGVL--LKLALLALPLLLLLSTPPCAPQVSGIRGDALERFCLQQPLDCDDIYAQGYQSDGVYL 80

  Fly    83 LKVPGLS-PFQVYCENQLAGPGWIVIQKRFSGNLSFFRNWKEYKNGFGNLMDEYFLGLEKIRALT 146
            :...|.| |..|:|:....|..|.|.||||:|::||||.|.:||.|||....||:|||:.:..||
Human    81 IYPSGPSVPVPVFCDMTTEGGKWTVFQKRFNGSVSFFRGWNDYKLGFGRADGEYWLGLQNMHLLT 145

  Fly   147 ALEPHELYVHLEDFDDTIKHAKFDEF-----AIGNEDDDYAMNTLGKYSGTAGDSLRSHRKMKFS 206
            ..:.:||.|.||||::...:||:.:|     |:..|:|.|.:...|...|.|||||..|...|||
Human   146 LKQKYELRVDLEDFENNTAYAKYADFSISPNAVSAEEDGYTLFVAGFEDGGAGDSLSYHSGQKFS 210

  Fly   207 TYDRDNDHEFNKNCAFYYLGGWWYNACLDSNLNGQYMPGGKYEESLFARGMCWRSWRGHNYGYRV 271
            |:|||.| .|.:|||....|.:|:.:|..:||||.|:.|....   :|.|:.|..|:|..|..:.
Human   211 TFDRDQD-LFVQNCAALSSGAFWFRSCHFANLNGFYLGGSHLS---YANGINWAQWKGFYYSLKR 271

  Fly   272 TQMMIR 277
            |:|.||
Human   272 TEMKIR 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30280	NP_611641.6	FReD	65..279	CDD:238040	87/228 (38%)
MFAP4	NP_001185624.1	FReD	60..278	CDD:238040	87/222 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	186	1.000	Domainoid score	I3350
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	188	1.000	Inparanoid score	I3915
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000029
OrthoInspector	1	1.000	-	-		otm40314
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19143
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	6.060