DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30280 and tnr

DIOPT Version :9

Sequence 1:	NP_611641.6	Gene:	CG30280 / 37522	FlyBaseID:	FBgn0050280	Length:	288	Species:	Drosophila melanogaster
Sequence 2:	NP_919364.1	Gene:	tnr / 369191	ZFINID:	ZDB-GENE-030804-1	Length:	1350	Species:	Danio rerio

Alignment Length:	262	Identity:	101/262 - (38%)
Similarity:	148/262 - (56%)	Gaps:	29/262 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 LEAIYEQAENALSTLQESLLQ----LETNGTLNTS---PDVIYPT--SC---LTSGDLENGLHTL 83
            ||.:.|..|..:.      ||    |||:..::||   .:.::||  :|   |.:|:...|::|:
Zfish  1089 LEGLAETTEYTVR------LQVARGLETSVIVSTSFTTGNRLFPTPQNCAQHLLNGETLGGIYTI 1147

  Fly    84 KV-PGLSP-FQVYCENQLAGPGWIVIQKRFSGNLSFFRNWKEYKNGFGNLMDEYFLGLEKIRALT 146
            .| ..||. .||||:....|.||||.|:|.:|...|.|.|.:||.|||:|.||::|||:.|..:.
Zfish  1148 YVNRDLSQGVQVYCDMTTDGGGWIVFQRRQNGLTDFSRKWTDYKIGFGSLEDEFWLGLDNIHKIA 1212

  Fly   147 ALEPHELYVHLEDFDDTIKHAKFDEFAIGNEDDDYAMNTLGKYSGTAGDSLRSHRKMKFSTYDRD 211
            |...:||.:.::|..::: :|.:|.|:||:....|.:. :|:|||||||||..|:...|||.|:|
Zfish  1213 AQGRYELRIDMKDGQESV-YANYDRFSIGDSKSLYKLR-IGEYSGTAGDSLSYHQSRPFSTKDKD 1275

  Fly   212 NDHEFNKNCAFYYLGGWWYNACLDSNLNGQYMPGGKYEESLFARGMCWRSWRGHNYGYRVTQMMI 276
            ||.... |||..|.|.|||..|..:|||      |||.||..::|:.|..|:||.:.....:|.:
Zfish  1276 NDIAVT-NCALSYKGAWWYKNCHRANLN------GKYGESRHSQGINWYHWKGHEFSIPFVEMKM 1333

  Fly   277 RP 278
            ||
Zfish  1334 RP 1335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30280	NP_611641.6	FReD	65..279	CDD:238040	90/221 (41%)
tnr	NP_919364.1	EGF_2	199..225	CDD:285248
		EB	234..283	CDD:279949
		EGF_2	294..318	CDD:285248
		fn3	323..401	CDD:278470
		fn3	411..490	CDD:278470
		fn3	500..579	CDD:278470
		FN3	590..674	CDD:238020
		fn3	682..754	CDD:278470
		fn3	771..849	CDD:278470
		FN3	859..935	CDD:214495
		fn3	949..1019	CDD:278470
		fn3	1035..1103	CDD:278470	4/19 (21%)
		FReD	1126..1336	CDD:238040	90/219 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100073
Panther	1	1.100	-	-	O	PTHR19143
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.910