DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30280 and Fga

DIOPT Version :9

Sequence 1:	NP_611641.6	Gene:	CG30280 / 37522	FlyBaseID:	FBgn0050280	Length:	288	Species:	Drosophila melanogaster
Sequence 2:	NP_001008724.1	Gene:	Fga / 361969	RGDID:	2603	Length:	782	Species:	Rattus norvegicus

Alignment Length:	301	Identity:	107/301 - (35%)
Similarity:	160/301 - (53%)	Gaps:	47/301 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 VPVFSVCIALSVMIFCHAETLNLFGNLEAIYEQAENALSTL-QESLLQLETNG---TLNTSPDVI 65
            ||.||          ..::|..:...:...|:.|:.|.|.. ||...:....|   |:....||:
  Rat   498 VPEFS----------SSSKTSTVRKQVTKSYKMADEAASEAHQEGDTRTTKRGRARTMRDCDDVL 552

  Fly    66 --YPTSCLTSGDLENGLHTLKVPGLSP-FQVYCENQLAGPGWIVIQKRFSGNLSFFRNWKEYKNG 127
              :|:..      :||:.::|:||.|. |.|||:.:.:..||::||:|..|:|:|.|.|::||.|
  Rat   553 QTHPSGA------QNGIFSIKLPGSSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRG 611

  Fly   128 FGNLMD----EYFLGLEKIRALTALEPHELYVHLEDFDDTIKHAKFDEFAIGNEDDDYAMNTLGK 188
            ||:|.|    |::||.:.:..|| |....|.|.|||:.....:|:: .|.:|:|.:.||:. :..
  Rat   612 FGSLNDKGEGEFWLGNDYLHLLT-LRGSVLRVELEDWAGKEAYAEY-HFRVGSEAEGYALQ-VSS 673

  Fly   189 YSGTAGDSL-----------RSHRKMKFSTYDRDNDHEFNKNCAFYYLGGWWYNACLDSNLNGQY 242
            |.|||||:|           .||..|:|||:|||.| ::.:|||..|.||||||:|..:||||.|
  Rat   674 YQGTAGDALMEGSVEEGTEYTSHSNMQFSTFDRDAD-QWEENCAEVYGGGWWYNSCQAANLNGIY 737

  Fly   243 MPGGKYEES-----LFARGMCWRSWRGHNYGYRVTQMMIRP 278
            .|||.|:..     ....|:.|..:||.:|..|..:|.|||
  Rat   738 YPGGTYDPRNNSPYEIENGVVWVPFRGADYSLRAVRMKIRP 778

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30280	NP_611641.6	FReD	65..279	CDD:238040	92/237 (39%)
Fga	NP_001008724.1	Fib_alpha	51..189	CDD:285864
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	264..374
		Fibrinogen_aC	388..453	CDD:288972
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	522..542		5/19 (26%)
		FReD	546..779	CDD:238040	94/243 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910