DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30280 and tnn

DIOPT Version :9

Sequence 1:	NP_611641.6	Gene:	CG30280 / 37522	FlyBaseID:	FBgn0050280	Length:	288	Species:	Drosophila melanogaster
Sequence 2:	XP_005171321.1	Gene:	tnn / 30234	ZFINID:	ZDB-GENE-990415-262	Length:	1020	Species:	Danio rerio

Alignment Length:	219	Identity:	78/219 - (35%)
Similarity:	118/219 - (53%)	Gaps:	15/219 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 YPTSC---LTSGDLENGLHTLKVPG--LSPFQVYCENQLAGPGWIVIQKRFSGNLSFFRNWKEYK 125
            :|..|   :.:|::|:|::|:.|..  ....||||:.:..|.||||.|:|.:|.:.|.:.|::|.
Zfish   793 FPMDCTQIMRNGNMESGVYTIYVNNNRSRTMQVYCDMKTDGGGWIVFQRRNTGKVDFMKKWRDYM 857

  Fly   126 NGFGNLMDEYFLGLEKIRALT-ALEPHELYVHLEDFDDTIKHAKFDEFAIGNEDDDYAMNTLGKY 189
            .|||.|.:|::|||:||..|| ....:|....|....|. |:|.:|.|.:......:.: |:|.|
Zfish   858 KGFGELTEEFWLGLDKIHELTNTPTQYEARFDLGSGSDR-KYAVYDNFKVAPSKQKFKL-TIGSY 920

  Fly   190 SGTAGDSLRSHRKMKFSTYDRDNDHEFNKNCAFYYLGGWWYNACLDSNLNGQYMPGGKYEESLFA 254
            .|.|||::..|:...|||.|.|||.... |||..:.|.|||..|..:||||::   |....|:
Zfish   921 KGNAGDAMTYHQGAPFSTVDSDNDIALG-NCALTHQGAWWYKNCHLANLNGRF---GDNRHSM-- 979

  Fly   255 RGMCWRSWRGHNYGYRVTQMMIRP 278
             |:.|..|:||.......::.|||
Zfish   980 -GVNWEPWKGHLQSLDFAEIKIRP 1002

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30280	NP_611641.6	FReD	65..279	CDD:238040	78/219 (36%)
tnn	XP_005171321.1	EGF_alliinase	<133..163	CDD:282688
		EGF_2	161..189	CDD:285248
		EGF_2	193..220	CDD:285248
		EGF_2	224..251	CDD:285248
		fn3	257..333	CDD:278470
		fn3	344..426	CDD:278470
		fn3	435..514	CDD:278470
		fn3	523..602	CDD:278470
		fn3	611..683	CDD:278470
		fn3	699..773	CDD:278470
		FReD	792..1003	CDD:238040	78/219 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100073
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810