DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30280 and tncb

DIOPT Version :9

Sequence 1:	NP_611641.6	Gene:	CG30280 / 37522	FlyBaseID:	FBgn0050280	Length:	288	Species:	Drosophila melanogaster
Sequence 2:	NP_001299845.1	Gene:	tncb / 30037	ZFINID:	ZDB-GENE-980526-104	Length:	1811	Species:	Danio rerio

Alignment Length:	222	Identity:	89/222 - (40%)
Similarity:	127/222 - (57%)	Gaps:	16/222 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 VIY--PTSC---LTSGDLENGLHTLKVPG--LSPFQVYCENQLAGPGWIVIQKRFSGNLSFFRNW 121
            |:|  |..|   |.:||..:||:|:.:.|  ..|.||||:....|.||||..:|.||.:.|||||
Zfish  1586 VLYKHPKDCSQALLNGDTTSGLYTIYLRGDESQPLQVYCDMTTDGGGWIVFVRRQSGKVEFFRNW 1650

  Fly   122 KEYKNGFGNLMDEYFLGLEKIRALTALEPHELYVHLEDFDDTIKHAKFDEFAIGNEDDDYAMNTL 186
            |.|..|||:|.||::|||..:..:|:...:||.|.|.|..:: .:|::|:|:|......|.:: :
Zfish  1651 KNYTAGFGDLNDEFWLGLSNLHKITSFGQYELRVDLRDKGES-AYAQYDKFSISEPRARYKVH-V 1713

  Fly   187 GKYSGTAGDSLRSHRKMKFSTYDRDNDHEFNKNCAFYYLGGWWYNACLDSNLNGQYMPGGKYEES 251
            |.||||||||:..|....|||||.|||.... |||..|.|.:||..|...|:.      |:|.::
Zfish  1714 GGYSGTAGDSMTYHHGRPFSTYDNDNDIAVT-NCALSYKGAFWYKNCHRVNIM------GRYGDN 1771

  Fly   252 LFARGMCWRSWRGHNYGYRVTQMMIRP 278
            ..::|:.|..|:||.:.....:|.|||
Zfish  1772 SHSKGVNWFHWKGHEHSVEFAEMKIRP 1798

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30280	NP_611641.6	FReD	65..279	CDD:238040	88/221 (40%)
tncb	NP_001299845.1	DnaJ	<471..>544	CDD:333066
		fn3	689..760	CDD:306538
		fn3	778..858	CDD:306538
		fn3	868..948	CDD:306538
		FN3	958..1047	CDD:238020
		fn3	1050..1128	CDD:306538
		fn3	1140..1215	CDD:306538
		fn3	1231..1303	CDD:306538
		fn3	1323..1400	CDD:306538
		fn3	1410..1482	CDD:306538
		fn3	1498..1570	CDD:306538
		FReD	1589..1798	CDD:238040	85/217 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100073
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810