DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30280 and Angptl2

DIOPT Version :9

Sequence 1:	NP_611641.6	Gene:	CG30280 / 37522	FlyBaseID:	FBgn0050280	Length:	288	Species:	Drosophila melanogaster
Sequence 2:	NP_598253.2	Gene:	Angptl2 / 171100	RGDID:	620004	Length:	493	Species:	Rattus norvegicus

Alignment Length:	252	Identity:	100/252 - (39%)
Similarity:	140/252 - (55%)	Gaps:	17/252 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 QAENALSTLQESLLQLETNGTLNTSPDVIYPT----SCLTSGDLENGLHTLKVPGLSP------F 91
            |::..|..|..||..:....:|.:|.|  .|:    .||.:  ||:|..|..:..:.|      .
  Rat   243 QSDQNLKVLPPSLPTMPALTSLPSSTD--KPSGPWRDCLQA--LEDGHSTSSIYLVKPENTNRLM 303

  Fly    92 QVYCENQLAGPGWIVIQKRFSGNLSFFRNWKEYKNGFGNLMDEYFLGLEKIRALTALEPHELYVH 156
            ||:|:.:....||.|||:|..|:::|||||:.||.||||:..||:||||.|..||....::|.|.
  Rat   304 QVWCDQRHDPGGWTVIQRRLDGSVNFFRNWETYKQGFGNIDGEYWLGLENIYWLTNQGNYKLLVT 368

  Fly   157 LEDFDDTIKHAKFDEFAIGNEDDDYAMNTLGKYSGTAGDSLRSHRKMKFSTYDRDNDHEFNKNCA 221
            :||:......|::..|.:..|.:.|.:. ||:|.|.||||...|...:|:|.|||:| .:..|||
  Rat   369 MEDWSGRKVFAEYASFRLEPESEYYKLR-LGRYHGNAGDSFTWHNGKQFTTLDRDHD-VYTGNCA 431

  Fly   222 FYYLGGWWYNACLDSNLNGQYMPGGKYEESLFARGMCWRSWRGHNYGYRVTQMMIRP 278
            .|..||||||||..|||||.:..||.| .|.:..|:.|..:||.:|..:...|||||
  Rat   432 HYQKGGWWYNACAHSNLNGVWYRGGHY-RSRYQDGVYWAEFRGGSYSLKKVVMMIRP 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30280	NP_611641.6	FReD	65..279	CDD:238040	92/224 (41%)
Angptl2	NP_598253.2	t_SNARE	156..>206	CDD:197699
Angptl2	NP_598253.2	FReD	273..487	CDD:238040	89/218 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	186	1.000	Domainoid score	I3251
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm12326
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.910