DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30280 and angptl3

DIOPT Version :9

Sequence 1:	NP_611641.6	Gene:	CG30280 / 37522	FlyBaseID:	FBgn0050280	Length:	288	Species:	Drosophila melanogaster
Sequence 2:	NP_571893.2	Gene:	angptl3 / 114421	ZFINID:	ZDB-GENE-010817-3	Length:	466	Species:	Danio rerio

Alignment Length:	230	Identity:	84/230 - (36%)
Similarity:	128/230 - (55%)	Gaps:	6/230 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 LETNGTLNTSPDVIYPTSC---LTSGDLENGLHTLKVPGLSPFQVYCENQLAGPGWIVIQKRFSG 113
            |.||.|..|.....:|..|   .|.|...:|::.:|.....||.||||....|.. .|||:|..|
Zfish   235 LTTNSTNGTKDINDFPADCSEVFTRGQKTSGIYPIKPNQSEPFYVYCEITPDGAA-TVIQRREDG 298

  Fly   114 NLSFFRNWKEYKNGFGNLMDEYFLGLEKIRALTALEPHELYVHLEDFDDTIKHAKFDEFAIGNED 178
            ::.|.::|::|::|||.|..|::|||.||.::.....:.|::.|||:.:..:..:: .|.:....
Zfish   299 SVDFDQSWEKYEHGFGKLEKEFWLGLAKIHSIAQQGEYILHIELEDWKEEKRFIEY-TFTLEGPA 362

  Fly   179 DDYAMNTLGKYSGTAGDSLRSHRKMKFSTYDRDNDHEFNKNCAFYYLGGWWYNACLDSNLNGQYM 243
            .|||:: |...||...|::.:|..|||||.|||||:....|||..|.||||::||.|:||||:|.
Zfish   363 SDYALH-LAPLSGDLSDAMSNHTGMKFSTKDRDNDNHDESNCARNYTGGWWFDACGDTNLNGRYA 426

  Fly   244 PGGKYEESLFARGMCWRSWRGHNYGYRVTQMMIRP 278
            ...........:|:.||..:|.:|..:.|::.|||
Zfish   427 WMRSKARHQRRKGIYWRPSKGSSYTLKSTKITIRP 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30280	NP_611641.6	FReD	65..279	CDD:238040	79/217 (36%)
angptl3	NP_571893.2	SMC_N	<111..>209	CDD:330553
angptl3	NP_571893.2	FReD	248..461	CDD:238040	77/215 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910