DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30280 and tnr

DIOPT Version :9

Sequence 1:	NP_611641.6	Gene:	CG30280 / 37522	FlyBaseID:	FBgn0050280	Length:	288	Species:	Drosophila melanogaster
Sequence 2:	NP_001107287.1	Gene:	tnr / 100135076	XenbaseID:	XB-GENE-948286	Length:	1350	Species:	Xenopus tropicalis

Alignment Length:	256	Identity:	92/256 - (35%)
Similarity:	138/256 - (53%)	Gaps:	17/256 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 LEAIYEQAENALSTL--QESLLQLETNGTLNTSPDVI-YPTSC---LTSGDLENGLHTLKVPG-- 87
            ||.:.|..|..:|.|  |.......|:....|...|. ||..|   :.:||.::|::.:.:.|
Frog  1091 LEGLLESTEYTVSILSVQNGERSSVTHTVFTTGGRVFSYPQDCAQHMLNGDNQSGVYYIYINGDM 1155

  Fly    88 LSPFQVYCENQLAGPGWIVIQKRFSGNLSFFRNWKEYKNGFGNLMDEYFLGLEKIRALTALEPHE 152
            .....|||:......||||.|:|.:|...|||.|.:|:.|||||.||::|||:.:..:|:...:|
Frog  1156 SQSVPVYCDMATDAGGWIVFQRRQNGLTDFFRKWADYRVGFGNLEDEFWLGLDTLHQVTSQGRYE 1220

  Fly   153 LYVHLEDFDDTIKHAKFDEFAIGNEDDDYAMNTLGKYSGTAGDSLRSHRKMKFSTYDRDNDHEFN 217
            |.:.:.|..:.: :|.:::|.||:....|.:. :|.::||:||||..|:...|||.|||||....
Frog  1221 LRIDMRDGQEAV-YAYYNKFNIGDARSLYKLR-IGDFNGTSGDSLTYHQGRPFSTKDRDNDVAVT 1283

  Fly   218 KNCAFYYLGGWWYNACLDSNLNGQYMPGGKYEESLFARGMCWRSWRGHNYGYRVTQMMIRP 278
             |||..|.|.|||..|..:|||      |||.||..::|:.|..|:||.:.....:|.:||
Frog  1284 -NCASSYKGAWWYKNCHRTNLN------GKYGESRHSQGINWYHWKGHEFSIPFVEMKMRP 1337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30280	NP_611641.6	FReD	65..279	CDD:238040	82/220 (37%)
tnr	NP_001107287.1	EGF_alliinase	153..196	CDD:282688
		EGF_2	198..223	CDD:285248
		EGF_2	260..285	CDD:285248
		EGF_2	292..316	CDD:285248
		FN3	321..410	CDD:238020
		fn3	413..493	CDD:278470
		fn3	502..582	CDD:278470
		FN3	592..676	CDD:238020
		fn3	684..763	CDD:278470
		fn3	773..840	CDD:278470
		fn3	862..939	CDD:278470
		fn3	949..1018	CDD:278470
		FN3	1037..1122	CDD:238020	8/30 (27%)
		FReD	1129..1337	CDD:238040	80/216 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	182	1.000	Domainoid score	I3392
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9330
Panther	1	1.100	-	-	O	PTHR19143
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010