DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30280 and angptl2

DIOPT Version :9

Sequence 1:	NP_611641.6	Gene:	CG30280 / 37522	FlyBaseID:	FBgn0050280	Length:	288	Species:	Drosophila melanogaster
Sequence 2:	NP_001090872.1	Gene:	angptl2 / 100038298	XenbaseID:	XB-GENE-488164	Length:	493	Species:	Xenopus tropicalis

Alignment Length:	251	Identity:	99/251 - (39%)
Similarity:	141/251 - (56%)	Gaps:	15/251 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 QAENALSTLQESL--LQLETNGTLNTSPDVIYP-TSCLTSGDLENGLHTLKVPGLSP------FQ 92
            |.:..|..|...|  :.|.|:.: ||:.....| ..||.:  ||:|..|..:..:.|      .|
Frog   243 QGDQNLKVLPPPLPTMPLFTSNS-NTTDKPSGPWKDCLQA--LEDGHDTSSIYLVKPENTNRLMQ 304

  Fly    93 VYCENQLAGPGWIVIQKRFSGNLSFFRNWKEYKNGFGNLMDEYFLGLEKIRALTALEPHELYVHL 157
            |:|:.:....||.|||:|..|:::|.|||:.||:||||:..||:||||.|..||..:.::|.|.:
Frog   305 VWCDQRHDPGGWTVIQRRLDGSVNFLRNWETYKHGFGNIDGEYWLGLENIYWLTNKDNYKLLVTM 369

  Fly   158 EDFDDTIKHAKFDEFAIGNEDDDYAMNTLGKYSGTAGDSLRSHRKMKFSTYDRDNDHEFNKNCAF 222
            ||:......|::..|.:..|.:.|.:. ||:|.|.||||...|...:|:|.|||:| .::.|||.
Frog   370 EDWSGRKVFAEYASFRLEPESEYYKLR-LGRYHGNAGDSFTWHNGKQFTTLDRDHD-VYSGNCAH 432

  Fly   223 YYLGGWWYNACLDSNLNGQYMPGGKYEESLFARGMCWRSWRGHNYGYRVTQMMIRP 278
            |..||||||||..|||||.:..||.| .|.:..|:.|..:||.:|..:...|||||
Frog   433 YQKGGWWYNACAHSNLNGVWYRGGHY-RSRYQDGVYWAEFRGGSYSLKKVVMMIRP 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30280	NP_611641.6	FReD	65..279	CDD:238040	91/221 (41%)
angptl2	NP_001090872.1	RILP-like	86..196	CDD:304877
angptl2	NP_001090872.1	FReD	273..487	CDD:238040	89/218 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm48348
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000