Protein Alignment Vrp1 and VRP1

DIOPT Version :9

• Sequence 1: NP_001097406.1
• Gene: Vrp1 / 37521
• FlyBaseID: FBgn0243516
• Length: 852
• Species: Drosophila melanogaster
• Sequence 2: NP_013441.1
• Gene: VRP1 / 851051
• SGDID: S000004329
• Length: 817
• Species: Saccharomyces cerevisiae
• Alignment Length: 952
• Identity: 223/952 - (23%)
• Similarity: 315/952 - (33%)
• Gaps: 352/952 - (36%)

  Fly     8 GPPPPPGPPPPPAMGGLKLGGAGGA-DARSALLSSIQKGTKLKKTTTVDKSGPALSGKVCGGDGG 71
            |.|.||.||||||:||.....|... ..|.|||..|:||.||||..|.|:|.|.:.|.|.....|
Yeast     3 GAPAPPPPPPPPALGGSAPKPAKSVMQGRDALLGDIRKGMKLKKAETNDRSAPIVGGGVVSSASG 67

  Fly    72 AGIGAKRTLNNNTSTSNHNNSSSSSNGLGNGTPKLGGLFEGLSQMPKLKPVNGIRAT-PSAGSAA 135
                      ::.:.|:...|.|:....|.|.|:||.:..|  .:||||.:|...:| ||..::|
Yeast    68 ----------SSGTVSSKGPSMSAPPIPGMGAPQLGDILAG--GIPKLKHINNNASTKPSPSASA 120

  Fly   136 TTTSKSTTNSSAQQRSNSP----PAATSASNASNGPM-DFNTELTKHLTLKRQKQ------QQQQ 189
            .....:..:.:|....|:|    ||..|..::|..|: |..:.....:.:.....      ....
Yeast   121 PPIPGAVPSVAAPPIPNAPLSPAPAVPSIPSSSAPPIPDIPSSAAPPIPIVPSSPAPPLPLSGAS 185

  Fly   190 QPQPPTNNTHINATEANLRTNR-----------GPPPQPPKSANSNDSILERMNIPRTAPTPPFG 243
            .|:.|.|..|:.:.....|:::           ..||.|..|..::.|     |.|:..|.||
Yeast   186 APKVPQNRPHMPSVRPAHRSHQRKSSNISLPSVSAPPLPSASLPTHVS-----NPPQAPPPPP-- 243

  Fly   244 NSSSVKAASPTLSDSGSNSSGSGGGSGSVKSKAANLNISLGNSFVNSSKSTVSAS----TASLNS 304
                    :||:               .:.||    ||...::.|:...|.|.|.    .|.:|:
Yeast   244 --------TPTI---------------GLDSK----NIKPTDNAVSPPSSEVPAGGLPFLAEINA 281

  Fly   305 SLTSSTGSVRNLAPNKSTLFGGSSGSSSGSSSGGGYASVHKSSPPSTADSTPSVTPT-PPPLQLP 368
            . .|..|:|..::..|.......|.|.....|         |:||......|.:.|| |||..||
Yeast   282 R-RSERGAVEGVSSTKIQTENHKSPSQPPLPS---------SAPPIPTSHAPPLPPTAPPPPSLP 336

  Fly   369 ---MKPAISFGKPNFAPKPPGLNQLAMANGQQRPAVTRHHSMKSPRSPPAAGIVNGLVFPTQQHL 430
               ..|..:...|  ||.||.| ..||::...       :|:|:...||
Yeast   337 NVTSAPKKATSAP--APPPPPL-PAAMSSAST-------NSVKATPVPP---------------- 375

  Fly   431 GTLRGPLQFHGSESSSPNTSAGSMRCAPNPPKSRPSVKPPPPPTPARSFSNTNLNNIGGSTMFSA 495
             ||..||         |||::    ..||...|.|:..|||||.|. :||
Yeast   376 -TLAPPL---------PNTTS----VPPNKASSMPAPPPPPPPPPG-AFS--------------- 410

  Fly   496 VNTALIQSSAISSQAPSPPITQPPSSSSSSNSVAALRDQFRGGAGMSNGAPSPPLPPTPAPSSNP 560
            .::||..||...:..|.||   |||.::|                    .||.| ||.|..::|.
Yeast   411 TSSALSASSIPLAPLPPPP---PPSVATS--------------------VPSAP-PPPPTLTTNK 451

  Fly   561 SSASASPKSLLRDNVKPIILNGGPL---------------------------------------- 585
            .|||:....:...:....:..||||
Yeast   452 PSASSKQSKISSSSSSSAVTPGGPLPFLAEIQKKRDDRFVVGGDTGYTTQDKQEDVIGSSKDDNV 516

  Fly   586 ---------NPP----------------------------APPPHR---------SCPPPP---P 601
                     |||                            |||||.         |.||||   .
Yeast   517 RPSPISPSINPPKQSSQNGMSFLDEIESKLHKQTSSNAFNAPPPHTDAMAPPLPPSAPPPPITSL 581

  Fly   602 PQRQSSNQDRVKYWIDK--TVYSFKKILHINRQGRHSGESVKVINMLNSKRNGGSGS-------- 656
            |...:|..|...   ||  ||...||.......|......|..:...:||.|..:.|
Yeast   582 PTPTASGDDHTN---DKSETVLGMKKAKAPALPGHVPPPPVPPVLSDDSKNNVPAASLLHDVLPS 643

  Fly   657 -------------------GSAPVPPQRH---------------------SSIRPNAPSTPPTHM 681
                               .|||..||:.                     .||..|...:||...
Yeast   644 SNLEKPPSPPVAAAPPLPTFSAPSLPQQSVSTSIPSPPPVAPTLSVRTETESISKNPTKSPPPPP 708

  Fly   682 ANASHQFGSSSGLS-------------------------------------SGSGAGAAASVGRL 709
            :.::...|:|:..|                                     |.|..||.:...|:
Yeast   709 SPSTMDTGTSNSPSKNLKQRLFSTGGSTLQHKHNTHTNQPDVDVGRYTIGGSNSIVGAKSGNERI 773

  Fly   710 VNDLETKFGKRFHNVTEFPKPPPFLNIQKVYPSRTFKATNAP 751
            |.| :::|  ::.||::.|||.||.|..|:|||.  |.::.|
Yeast   774 VID-DSRF--KWTNVSQMPKPRPFQNKTKLYPSG--KGSSVP 810

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vrp1	NP_001097406.1	None
VRP1	NP_013441.1	WH2_WAS_WASL	27..55	CDD:409207	14/27 (52%)
		PRK14951	<109..>240	CDD:237865	25/135 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344007
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4462
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53287
OrthoFinder	1	1.000	-	-		FOG0006482
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.800