Protein Alignment Vrp1 and wipf2b

DIOPT Version :9

• Sequence 1: NP_001097406.1
• Gene: Vrp1 / 37521
• FlyBaseID: FBgn0243516
• Length: 852
• Species: Drosophila melanogaster
• Sequence 2: NP_001002165.1
• Gene: wipf2b / 415255
• ZFINID: ZDB-GENE-040625-182
• Length: 441
• Species: Danio rerio
• Alignment Length: 786
• Identity: 179/786 - (22%)
• Similarity: 234/786 - (29%)
• Gaps: 387/786 - (49%)

  Fly     1 MAIPPPPGPPPPPGPPPPPAMGGL-----KLGGAGGADARSALLSSIQKGTKLKKTTTV-DKSGP 59
            |.||||  ||||.||||||.:...     || ....|..|.||||.|.||.:|||||.| |:|.|
Zfish     1 MPIPPP--PPPPAGPPPPPTLSQANTTPPKL-SRDEAKGRGALLSDICKGARLKKTTGVNDRSAP 62

  Fly    60 ALSGKVCGGDGGAGIGAKRTLNNNTSTSNHNNSSSSSNGLGNGTP--KLGGLFEGLSQMPKLKPV 122
            .:. |..||.||.                      ||:|.|:..|  .:||||:|  .:|||:||
Zfish    63 LIE-KPKGGGGGV----------------------SSSGGGSSAPVQPVGGLFQG--GVPKLRPV 102

  Fly   123 NGIRATPSA------GSAATTT--SKSTTNSSAQQRS---NSPPAATSASNASNGPMDFNTELTK 176
            ....|..||      .|||...  |:...:|.:||.|   :|.|...|..:.|..|...|:
Zfish   103 GDGSAGRSALHPHGTRSAAPRPPGSQEDPDSPSQQVSPPESSRPQRPSLPDLSRSPAGGNS---- 163

  Fly   177 HLTLKRQKQQQQQQPQPPTNNTHINATEANLRTNRGPPPQPPKS--ANSNDSILERMNIP---RT 236
                            |.|...|         ::..|||.||.|  .|:..:.|::.|.|   |.
Zfish   164 ----------------PSTGMKH---------SSSAPPPPPPMSRRGNAPPAPLQKANAPLYNRE 203

  Fly   237 APTPPFGNSSSVKAASPTLSDSGSNSSGSGGGSGSVKSKAANLNISLGNSFVNSSKSTVSASTAS 301
            .|.||
Zfish   204 KPLPP------------------------------------------------------------ 208

  Fly   302 LNSSLTSSTGSVRNLAPNKSTLFGGSSGSSSGSSSGGGYASVHKSSPPSTADSTPSVTPTPPPLQ 366
                    |...|..:|                      |.|.:::||      |.|.|.|.|..
Zfish   209 --------TPEQRGPSP----------------------APVRENAPP------PPVKPPPSPAS 237

  Fly   367 LPMKPAISFGKPNFAPKPPGLNQLA-MANGQQRPA-------VTRHHSMKSPRSPPAAGIVNGLV 423
               ..:.|....:.||.||...|.: ::||...|.       ..||:|:.  :.|.|||..
Zfish   238 ---SRSSSSSSSSLAPPPPPYRQQSGLSNGPSSPVNEAAPELPQRHNSLS--KKPSAAGHT---- 293

  Fly   424 FPTQQHLGTLRGPLQFHGSESSSPNTSAGSMRCAPNPPKSRPSVKPPPPPTPARSFSNTNLNNIG 488
             ||:.|.                             ||       |||.|||
Zfish   294 -PTRGHA-----------------------------PP-------PPPSPTP------------- 308

  Fly   489 GSTMFSAVNTALIQSSAISSQAPSPPITQPPSSSSSSNSVAALRDQFRGGAGMSNGAPSPPLPPT 553
                              .:..|.||..:||.               ||.|        ||:|..
Zfish   309 ------------------QAGRPPPPAREPPG---------------RGAA--------PPVPGQ 332

  Fly   554 PAPSSNPSSASASPKSLLRDNVKPIILNGGPLNPPAPPPHRSCPPPPPPQRQSSNQDRVKYWIDK 618
            |:.:.             ||               |||     |||||.:...::.|
Zfish   333 PSRNG-------------RD---------------APP-----PPPPPYRTHGTSSD-------- 356

  Fly   619 TVYSFKKILHINRQGRHSGESVKVINMLNSKRNGGSGSGSAPVPPQRHSSIRPNAPSTPPTHMAN 683
                                              ....|..|.||.|    .|..|..||..:.|
Zfish   357 ----------------------------------APSRGKPPPPPSR----TPAGPPPPPPPIRN 383

  Fly   684 ASHQFGSSSGLSSGSGAGAAASVGR-LVNDLETKFGKRFHNVTEFPKPPPFLNIQKVYPSRTFKA 747
            ..                  .|:.| .|:|.|:|:.  ||.:.:||.|..:.:..|:|||:..:|
Zfish   384 GH------------------TSISRSFVDDFESKYS--FHPLDDFPPPEEYRHFTKIYPSKANRA 428

  Fly   748 T--NAP 751
            .  .||
Zfish   429 VMRGAP 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vrp1	NP_001097406.1	None
wipf2b	NP_001002165.1	WH2	36..60	CDD:280384	15/23 (65%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4462
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	2	1.860