Protein Alignment Vrp1 and Wipf1

DIOPT Version :9

• Sequence 1: NP_001097406.1
• Gene: Vrp1 / 37521
• FlyBaseID: FBgn0243516
• Length: 852
• Species: Drosophila melanogaster
• Sequence 2: NP_001276651.1
• Gene: Wipf1 / 215280
• MGIID: 2178801
• Length: 493
• Species: Mus musculus
• Alignment Length: 781
• Identity: 185/781 - (23%)
• Similarity: 244/781 - (31%)
• Gaps: 329/781 - (42%)

  Fly     1 MAIPPPPGPPPPP----GPPPPPAMGGLKLGGAGGADARSALLSSIQKGTKLKKTTTVDKSGPAL 61
            |.:||||.|||||    .....|.:...:..|      |:||||.|.||.|||||.|.|:|.|.|
Mouse     1 MPVPPPPAPPPPPTFALANTEKPTLNKTEQAG------RNALLSDISKGKKLKKTVTNDRSAPIL 59

  Fly    62 -----SGKVCGGDGGAGIGAKRTLNNNTSTSNHNNSSSSSNGLGNGTPKLGGLFEGLSQMPKLKP 121
                 :|...||.||.|.|.        .........|..|..|.|.|.|||||:  :.||||
Mouse    60 DKPKGAGASAGGYGGGGGGG--------GGGGGGGGGSGGNFGGGGPPGLGGLFQ--AGMPKL-- 112

  Fly   122 VNGIRATPSAGSAATTTSKSTTNSSAQQRSNSPP------AATSASNAS--NGPMDFNTELTKHL 178
                              :||.|.......:.||      .||||...|  :||..|......|
Mouse   113 ------------------RSTANRDNDSGGSRPPILPPGGRATSAKPFSPPSGPGRFPAPSPGH- 158

  Fly   179 TLKRQKQQQQQQPQPPTNNTHINATEANLRTNRGPPPQPPKSANSNDSILERMNIPRTAPTPPFG 243
                    :...|:||              .||.|||:|...:.           |.:.| ||..
Mouse   159 --------RSGPPEPP--------------RNRMPPPRPDVGSK-----------PDSLP-PPVP 189

  Fly   244 NSSSVKAASPTLSDSGSNSSGSGGGSGSVKSKAANLNISLGNSFVNSSKSTVSASTASLNSSLTS 308
            |       :|....|..::.||..|.|:.:..
Mouse   190 N-------TPRPVPSSLHNRGSPAGLGAPRPP--------------------------------- 214

  Fly   309 STGSVRNLAPNKSTLFGGSSG--SSSGSSSGGGYASVHKSSPPSTADSTPSVTPTPPPLQLPMKP 371
                   ...|:...||..|.  :.|||||                       |.|.|   |:.|
Mouse   215 -------FPGNRGAAFGAGSARQNPSGSSS-----------------------PFPRP---PLPP 246

  Fly   372 AISFGKPNFAPKPPGLNQLAMANGQQRPAVTRHHSMKSPRSPPAAGIVNGLVFPTQQHLGTLRGP 436
            ..|....:..|.||             |.|....||.....||.         |:|    |.:.|
Mouse   247 TPSRALDDKPPPPP-------------PPVGNRPSMHREAVPPP---------PSQ----TSKPP 285

  Fly   437 LQFHGSESSSPNTSAGSMRCAPNPPKSRPSVKPPPPPTPARSFSNTNLNNIGGSTMFSAVNTALI 501
            :      .|:|....||....|.||.|||.   |||..||   ||..:..              :
Mouse   286 V------PSTPRPGLGSQAPPPPPPPSRPG---PPPLPPA---SNDEIPR--------------L 324

  Fly   502 QSSAISSQAPSPPITQPPSSSSSSNSVAALRDQFRGGAGMSNGAPSPPLPPTPAPSSNPSSASAS 566
            ....:|..:.:||:..|                  |.:|        ||||.|:.
Mouse   325 PQRNLSLTSSAPPLPSP------------------GRSG--------PLPPPPSE---------- 353

  Fly   567 PKSLLRDNVKPIILNGGPLNPPAP---PPHRSCP-PPPPPQRQSSNQDRVKYWIDKTVYSFKKIL 627
                               .||.|   ||.||.| |||||
Mouse   354 -------------------RPPPPVRDPPGRSGPLPPPPP------------------------- 374

  Fly   628 HINRQGRHSGESVKVINMLNSKRNGGSGSGSAPVPPQRHSSIRPNAPST----PPTHMANASHQF 688
             |||.| .:..::.....|.| |:|.....|.|.||     :.|:.|..    ||....:..:.|
Mouse   375 -INRNG-STARALPATPQLPS-RSGMDSPRSGPRPP-----LPPDRPGAGAPPPPPPSTSVRNGF 431

  Fly   689 GSSSGLSSGSGAGAAASVGRLVNDLETKFGKRFHNVTEFPKPPPFLNIQKVYPSRTFKATNAPGN 753
            ..||                ..::.|::|  .||.:::.|.|.|::...|.|||:..:..:..|:
Mouse   432 QDSS----------------CEDEWESRF--YFHPISDLPPPEPYVPTTKTYPSKLARNESRSGS 478

  Fly   754 S 754
            :
Mouse   479 N 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vrp1	NP_001097406.1	None
Wipf1	NP_001276651.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..493		185/781 (24%)
		WH2_WAS_WASL-1	29..60	CDD:409219	18/36 (50%)
		Binds actin. /evidence=ECO:0000250	45..48		2/2 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838529
Domainoid	1	1.000	77	1.000	Domainoid score	I8824
eggNOG	1	0.900	-	-		E1_KOG4462
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006482
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.790