Protein Alignment Vrp1 and wipf1a

DIOPT Version :10

• Sequence 1: NP_001097406.1
• Gene: Vrp1 / 37521
• FlyBaseID: FBgn0243516
• Length: 852
• Species: Drosophila melanogaster
• Sequence 2: NP_001121767.2
• Gene: wipf1a / 100005341
• ZFINID: ZDB-GENE-080204-101
• Length: 520
• Species: Danio rerio
• Alignment Length: 792
• Identity: 182/792 - (22%)
• Similarity: 241/792 - (30%)
• Gaps: 326/792 - (41%)

  Fly     6 PPGPPPPPGPPPPPAMGGLKLGGAGGAD--ARSALLSSIQKGTKLKKTTTVDKSGPALSGKVCGG 68
            |..|||||||||..:....:.......:  .|:||||.|.||.:||||.|.|:|||.|.....||
Zfish     2 PGPPPPPPGPPPTFSQANTEKPNLSRNEQQGRNALLSDINKGARLKKTITNDRSGPVLDKPKGGG 66

  Fly    69 DGGAGIGAKRTLNNNTSTSNHNNSSSSSNGLGNG-TPKLGGLFEGLSQMPKLKPV----NGIRA- 127
            .||.|.|                    ..|.|.| :..:||||:|  .||:||..    ..:||
Zfish    67 GGGGGGG--------------------GGGFGGGASGGMGGLFQG--GMPRLKSAGNRDGNVRAP 109

  Fly   128 -TPSAGSAATTTSKSTTNSSAQQRSNSPPAATSASNASNGPMDFNTELTKHLTLKRQKQQQQQQP 191
             .||.|       :....||...|..:|.:...:.....||                     .:|
Zfish   110 MPPSGG-------RFPAPSSPAGRFPAPSSPAGSRPPVPGP---------------------GRP 146

  Fly   192 QPPTNNTHINATEANLRTNRGPPPQPPKSANSNDSILERMNIPRTAPTPPFGNSSSVKAASPTLS 256
            .|               ...||||.|..|.:...|      .|...|..|.|.......|.|..:
Zfish   147 SP---------------GRAGPPPIPSSSRSPQHS------SPGGPPPIPGGRPQGSSPAPPPPN 190

  Fly   257 DSGSNSSGSGGGSGSVKSKAANLNISLGNSFVNSSKSTVSASTASLNSSLTSSTGSVRNLAPNKS 321
            .||..:                       ||....:.:.|:...                .|.:|
Zfish   191 SSGRRT-----------------------SFPQPPRESQSSFPP----------------PPRES 216

  Fly   322 TLFGGSSGSSSGSSSGGGYASVHKSSPPSTADSTPSVTPTPPPLQ--LPMKPAISFGKPNFAPKP 384
            |.                       .||....|.|     |||.:  .|..|..|    :|.|.|
Zfish   217 TF-----------------------PPPPRESSFP-----PPPRESSFPPPPRES----SFPPPP 249

  Fly   385 PGLNQLAMANGQQRPAVTRHHSMKSPRSPPAAGIVNGLVFPTQQHLGTLRGPLQFHGSESSSPNT 449
                                  .:|...||                     |.:.|.|....|..
Zfish   250 ----------------------RESSFPPP---------------------PRESHSSFPPPPRE 271

  Fly   450 SAGSMRCAPNPPKSRPSV-----KP-----PPPPTPARSFSNTNLNNIGGSTMFSAVNTALIQSS 504
            |..|....|.|...||.:     :|     ||||.||           ||            :..
Zfish   272 SQSSFPPPPIPASGRPPLPSIPGRPQADDFPPPPPPA-----------GG------------RRE 313

  Fly   505 AISSQAPSPPITQPPSSSSSSNSVAALRDQFRGGAGMSNGAPS-PP----LPPTPAPSSNP--SS 562
            :.....|.|    ||..|:....:.:.|.       |.|..|| ||    .||.| |||..  ||
Zfish   314 SFCRDGPLP----PPPPSTECKPMGSQRP-------MGNAPPSLPPGRGGAPPIP-PSSRDELSS 366

  Fly   563 ASASPKSLLRDNVKPIILNGGPLNPPAPPPHRSCPPPPPPQRQSSNQDRVKYWIDKTVYSFKKIL 627
            ..||..||                ||.|||.|:.|.||||.
Zfish   367 RGASRNSL----------------PPPPPPGRTSPLPPPPS------------------------ 391

  Fly   628 HINRQGRHSGESVKVINMLNSKRNGGS-GSGSAPVPPQ-------RHSSI----RPNAPSTPPTH 680
              |.:...:|:|.:..::......||: |....||||.       |.|.:    .|..||.||..
Zfish   392 --NERPPPTGKSARSGSLPPPPPAGGNRGGAPPPVPPPNRPGGSGRPSLVPDPPAPRVPSFPPAP 454

  Fly   681 MANASHQFGSSSGLSSGSGAGAAASVGRLVNDLETKFGKR--FHNVTEFPKPPPFLNIQKVYPSR 743
            .:::.:.:....                  ..:..::|.|  ||:::|.|.|.|:::..|.|||:
Zfish   455 PSDSINGYQCPP------------------PPVSDEWGMRFSFHSLSELPPPEPYVSFSKSYPSK 501

  Fly   744 T----FKATNAP 751
            :    .|...||
Zfish   502 SGGKGIKDRGAP 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vrp1	NP_001097406.1	None
wipf1a	NP_001121767.2	WH2_WAS_WASL-1	29..60	CDD:409219	17/30 (57%)
		actin-binding sequence	46..49	CDD:409219	2/2 (100%)
		PHA03247	<108..468	CDD:223021	120/617 (19%)