Protein Alignment Plekhm1 and Def8

DIOPT Version :9

• Sequence 1: NP_611639.1
• Gene: Plekhm1 / 37520
• FlyBaseID: FBgn0034694
• Length: 720
• Species: Drosophila melanogaster
• Sequence 2: NP_001019945.1
• Gene: Def8 / 307973
• RGDID: 1309008
• Length: 451
• Species: Rattus norvegicus
• Alignment Length: 476
• Identity: 126/476 - (26%)
• Similarity: 202/476 - (42%)
• Gaps: 104/476 - (21%)

  Fly   280 NEEQTGGDKAE--TNETAEQEAPSGSKTRSRKKSNRQMDSSSFAD-------------------- 322
            :.||...:||:  |:|....|.|:|.....  .|.|.||.....|
  Rat    26 HHEQEPNEKAQEVTSEDTLPELPAGEPEFC--YSERMMDLGLSEDHFSRPVGLFLASDVQQLRQA 88

  Fly   323 ------LDLEAPSLLPQGSNSLSNLMQTSWS-GDLEATPTSPTEE------LTGSRFF-QRSVSV 373
                  :.||.|....:..:::..|:..... .:|:    .|.||      |...||: ::|.||
  Rat    89 IEECKQVILELPEQSEKQKDAVVRLIHLRLKLQELK----DPNEEEPNIRVLLEHRFYKEKSKSV 149

  Fly   374 SSSVSLRSPTTDRCSYNALLRKHESNRESGAGWS--EIWEK-----FRASASNLNVAQPQRDTDP 431
            ..       |.|:|  |.::            |.  :.|..     :|..:..||:.     :.|
  Rat   150 KQ-------TCDKC--NTII------------WGLIQTWYTCTGCYYRCHSKCLNLI-----SRP 188

  Fly   432 PISEDLSDLQSLDTNSEFELLTSEFDMVELQQMVAQLCQLAREPGLDAQGFLCKSCQHPLGI-GY 495
            .:|..:|.      .:|:||               .:|.   |.|||:|.:.|..|:.|:.: |.
  Rat   189 CVSSKVSH------QAEYEL---------------NICP---ETGLDSQDYRCAECRAPISLRGV 229

  Fly   496 -SNFQVCAFSGSYYCNSCMDVEMQLIPARIIYNWDFRKYSVSKRAATFLAEFRSHPFLDMQLLNP 559
             |..:.|.::|.|||:.|...::.:||||:::||||....||:.:..:||...|.|.|.::.:||
  Rat   230 PSEARQCDYTGQYYCSHCHWNDLAVIPARVVHNWDFEPRKVSRCSMRYLALMVSRPVLRLREINP 294

  Fly   560 RIYFASDAMAELQSLRIRLNFIRAYLYTCAPSSIELLQNQFAGREYLYEHIHLYSIADLALIQRG 624
            .::...:.:.|::.||..:..::.|..||..:....|..|...|::..|:..:|||.||..:..|
  Rat   295 LLFNYVEELVEIRKLRQDILLMKPYFITCKEAMEARLLLQLQDRQHFVENDEMYSIQDLLEVHMG 359

  Fly   625 VLCQQLQKAFKLGEAHV-LKCRLCHLKGFICEICQSPRVLYPFHISTTFRCLACGAVFHAEC-LN 687
            .|...|.:...:...|: |.|..|..|||:||:|:...||:||. |.|..|..|.||||.:| .:
  Rat   360 RLSCSLTEIHTIFAKHIKLDCERCQAKGFVCELCKEGDVLFPFD-SHTSVCNDCSAVFHRDCYYD 423

  Fly   688 EKQPCPKCERIRKREDQGLQE 708
            ....||||.|:..|:....||
  Rat   424 NSTTCPKCARLTLRKQSLFQE 444

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Plekhm1	NP_611639.1	RUN	54..185	CDD:280855
		zf-RING_9	500..700	CDD:290612	69/201 (34%)
Def8	NP_001019945.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	18..48		7/21 (33%)
		C1_DEF8	134..194	CDD:410369	17/85 (20%)
		zf-RING_9	236..433	CDD:404739	68/197 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1829
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D177737at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820