Protein Alignment Plekhm1 and rubcn

DIOPT Version :10

• Sequence 1: NP_611639.1
• Gene: Plekhm1 / 37520
• FlyBaseID: FBgn0034694
• Length: 720
• Species: Drosophila melanogaster
• Sequence 2: XP_031757906.1
• Gene: rubcn / 100497647
• XenbaseID: XB-GENE-990005
• Length: 933
• Species: Xenopus tropicalis
• Alignment Length: 925
• Identity: 193/925 - (20%)
• Similarity: 328/925 - (35%)
• Gaps: 313/925 - (33%)

  Fly    55 LCTTLEALFLHGL---------KD--SFLSATFNVIAG---DVERRPEPSFWAPCMVFMHKQVIE 105
            ||..:.::|.|||         ||  :|:.::..:..|   .||:         .::|     .|
 Frog    47 LCRDMSSIFQHGLICDQVYCKQKDYWNFVKSSQRLHPGTSPQVEQ---------FLLF-----FE 97

  Fly   106 QVQGLSQITSETGQCRAWVRQSLNESVFSSYLNNMRKNGSALSQYYKRNALMRDSEGLETAAKIM 170
            ..|...:..||....:.|::.||.....|:.|..:..|.....::|..:|.:.....:....:.:
 Frog    98 NSQRNCENISEKDNGKLWLQHSLQFHCLSAQLKALLGNRQYTRKFYSESAFLLSEAHVAAMFQCL 162

  Fly   171 ESLE-------AYVQFDLPVNSSLLNHWPDYSLQLSDLWTPALKSCPISSGVDVASSLGSDIIAI 228
            |::|       |.:...:......|| ..:.||.||.|        |.|:|:....:
 Frog   163 EAVEQNNPRLLAQIDTSVLAGKRQLN-ISEKSLSLSTL--------PGSTGIPYTDN-------- 210

  Fly   229 PTPQPLQTNELFSESISNSPFGRNSNFGVPE-------LSQRENLDLLIQKFD------------ 274
             ||..|.::....:|.|       |:|.:.:       :|:.|::.:.:...|
 Frog   211 -TPHSLYSSYSSLQSFS-------SDFRIDQQNNLYRAVSENESIIVSVAPADDSPPHEAFSPVS 267

  Fly   275 EMDVINEEQTGGDKAETNETAEQEAPSG------------SKTRSRKKSN------RQMDS---- 317
            ||.|........| |.:.|....||..|            |.::|.:.||      ::.||
 Frog   268 EMSVSTLTSQSED-AGSPEDPHSEADDGPEYLAIGNMSRRSSSQSSESSNLFSCNSQKTDSLNST 331

  Fly   318 ---------------SSFADL------------------DLEAPSLLPQGSN-SLSNLMQ----T 344
                           |||:::                  |.......||||: ::|.:|:    .
 Frog   332 PTAPQNTCLLSVPRRSSFSEIQFGNGPWHTKKSHMRSRSDTNVTIGKPQGSDRNISIIMEDPAAE 396

  Fly   345 SWSGDLEATPT---------SP------------------------------TEELTGS------ 364
            |.|| |...|.         ||                              :|:..||
 Frog   397 SHSG-LRNNPALLGKNKAIGSPYIEHDSAPYLNTAEGVFRRPSKGQSLISYLSEQDFGSCADLEK 460

  Fly   365 --RFFQRSVSVSSSVSLRSPTTDRCSYNALLRK-HESNRESGAGWSEIWEKFRASASNL------ 420
              ..|..|.|:.:::.|.     :|  |.:.|: .|...:|.....|:.:|.|.....:
 Frog   461 ENAHFSISESLIAAIELM-----KC--NMISRQLQEEEEDSDREIRELKQKIRLRRQQIRSCRNQ 518

  Fly   421 -------NVAQPQRDTDPPISE----DLSDLQSLDTNSEFELLTSE------------------- 455
                   :.:|...::...||.    .:|:..|.|...::|:..||
 Frog   519 SAYTEGGSSSQGMTESGSQISSHESIPVSESSSADEVDQYEIKDSEIKRGLNSHHLQCTESMSHS 583

  Fly   456 -----------------FDMVEL----------------QQMV---------------AQLCQL- 471
                             |:.::|                |:::               |.:.:|
 Frog   584 FLCSNSAEAVAMGLLKQFEGMQLPAASELEWLVPEHDAPQKLLPIPDSVPISPDDGEHADIYKLR 648

  Fly   472 ------------------------AREPGLDAQGFLCKSCQHPLGIGY-SNFQVCAFSGSYYCNS 511
                                    .::..:..|.:.|..|...:...| ...:.|.:.|.|:|..
 Frog   649 IRVRGNLEWAPPRPQIIFNIHTAPTKKAAVTKQNYRCAGCGIRIESDYIKRLRYCEYLGKYFCQC 713

  Fly   512 CMDVEMQLIPARIIYNWDFRKYSVSKRAATFLAEFRSHPFLDMQLLNPRIYFASDAMAELQSLRI 576
            |.:....:||.|||..|||.||.||..:...|.:..|.|..::|.:|..:|....|:.:::.|||
 Frog   714 CHENAQSVIPGRIIRKWDFSKYYVSNFSKDLLTKIWSDPLFNLQDINSPLYRKVKALEQVRLLRI 778

  Fly   577 RLNFIRAYLYTC--APSSIELLQNQFAGREYLYEHIHLYSIADLALIQRGVLCQQLQKAFKLGEA 639
            :|..::....||  |...:| |.:...|  :|.|..||:|::||..|::|.|..:|:...|.|..
 Frog   779 QLVHLKNMFKTCRLAKGILE-LYDIVPG--HLTEDHHLFSLSDLTSIKKGELVPRLRDLVKSGAL 840

  Fly   640 HVLKCRLCHLKGFICEICQS-PRVLYPFHISTTFRCLACGAVFHAECLNEKQPCPKCERIRKRED 703
            ||.||.||..||||||.||: ..|::||.::...||..|.|.:|..|...:: ||||||:|.|.|
 Frog   841 HVEKCMLCQAKGFICEFCQNEDDVIFPFELNKCRRCEDCKACYHKYCFRSEE-CPKCERLRARRD 904

  Fly   704 QGLQEAVQCLKQKNE 718
            ...:::::......|
 Frog   905 LLAKQSLESYNSDQE 919

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Plekhm1	NP_611639.1	RUN_PLEKHM1	20..191	CDD:439041	30/156 (19%)
		zf-RING_9	500..700	CDD:464030	76/202 (38%)
rubcn	XP_031757906.1	RUN_RUBCN	24..180	CDD:439048	28/146 (19%)
		zf-RING_9	701..901	CDD:464030	76/203 (37%)