Protein Alignment Plekhm1 and rubcnl

DIOPT Version :10

• Sequence 1: NP_611639.1
• Gene: Plekhm1 / 37520
• FlyBaseID: FBgn0034694
• Length: 720
• Species: Drosophila melanogaster
• Sequence 2: NP_001190195.1
• Gene: rubcnl / 100497231
• XenbaseID: XB-GENE-6046118
• Length: 806
• Species: Xenopus tropicalis
• Alignment Length: 730
• Identity: 164/730 - (22%)
• Similarity: 272/730 - (37%)
• Gaps: 173/730 - (23%)

  Fly    80 AGDVERRPEPSFWAPCMVFMHKQVIEQVQGLSQITSETGQCRAWVRQSLNESVFSSYLNNMRKNG 144
            ||..:....||..|..:.|:...:..:.|.:|.|||:..              ||
 Frog   124 AGPSDLITAPSTAANALPFLKPDLCTEGQNISDITSQVN--------------FS---------- 164

  Fly   145 SALSQYYKRNALMRDSEGLETAAKIMESLE-AYVQFDLPVNSSLLN---HWPDYSLQLSDLWTPA 205
                           ..||:..|:...|.. |.:.||    .|::|   ..||..|..:||.:..
 Frog   165 ---------------GTGLQREARRFSSPNIASLCFD----QSMINCTTAIPDLPLSTADLHSKD 210

  Fly   206 LKSCPISSGVDVASSLGSDIIAIPTPQPLQTNELFSESISNS--PF----GRNSNFGVPEL--SQ 262
            :|.....|     .|..|.:.|:.|.....| |:..:|..|:  |.    ..|::..|.:|  |.
 Frog   211 IKLVRRRS-----QSFSSILKALDTSLTGST-EILHQSTENTFEPTVNLENENAHLLVADLFISV 269

  Fly   263 RENLDLLIQKFDEMDVINEEQTGGDKAETNE-----TAEQEAPSGSKTR---------------- 306
            .|||...:|......||.|.:....::..|.     |..|:.||.|...
 Frog   270 VENLKSRLQSMHYEQVIAERRPSCSRSCKNHPMNLFTPRQKIPSESAASVDSGYEGLVAMQHNFP 334

  Fly   307 ----SRKKSNRQMDSSSFADL---DLEAPSLL----------------------PQGSNSLSNLM 342
                :...|....:..||.|.   :||.|::.                      ||.       |
 Frog   335 ADSFTEHSSKLYSEWPSFTDATVEELEHPAVWHNSPMDYISEPDSKHRALWQNPPQD-------M 392

  Fly   343 QTSWSGDLEATPTSPTEELTGSRFFQRSVSVSSSVSLRSPTTDRC----SYNALL------RKHE 397
            .|:.......:|:|...|.....:.:...|.:::.:..|.....|    .||..:      .|.|
 Frog   393 STAHDSKDTVSPSSDHVEKAAKYYAEWQKSTNNTANYNSKCCWVCEGCNEYNEFVIIEMIDDKKE 457

  Fly   398 SNRESGA-----------------------GWSEIWEKFRASASNLNVAQPQRDTDPP-ISEDLS 438
            :..||.|                       .:.:.|.::.|..:.:....|..:.:.. :.|:|.
 Frog   458 AAMESSAEMERDIPAPGSNSAEQTLKKLYRAFRQQWLQYEAEMALVGPPAPNTEKNNDFLPEELE 522

  Fly   439 DLQSLDTNSEFELLTSEFDMVELQQMVAQLCQL--------AREPGLDAQGFLCKSCQHPLGIGY 495
              .||....|.:    :|.|.|.::......|:        .|:..:.:|.::|..|...:...|
 Frog   523 --SSLTLAEEIK----KFRMREAEEWAPPRFQIINTINPSPKRDVIVASQNYMCAGCGTKVEPRY 581

  Fly   496 SN-FQVCAFSGSYYCNSCMDVEMQLIPARIIYNWDFRKYSVSKRAATFL-AEFRSHPFLDMQLLN 558
            :| .:.|.:.|.|:|:.|.......||:||:..::|.||.||..:...: :.::||.| ::...|
 Frog   582 TNRLRYCEYLGKYFCDCCHSNAFSSIPSRILLKFNFGKYHVSNFSKNVVDSIWQSHKF-NVLSEN 645

  Fly   559 PRIYFASDAMAELQSLRIRLNFIRAYLYTCAPSSIELLQNQFAGR-EYLYEHIHLYSIADLALIQ 622
            |.||.....::.::.|:.||..::..|.||..:|..|  .:|... .:|.|.:.|::::||..::
 Frog   646 PDIYKKVKDLSRIKELQERLIPMKRLLCTCRFASSVL--KEFKDHPHHLTEELDLFTLSDLFNVK 708

  Fly   623 RGVLCQQLQKAFKLGEAHVLKCRLCHLKGFICEICQSPRVLYPFHISTTFRCLACGAVFHAECLN 687
            :.:|...|||......|||..|.||..||||||.|....|::||......||..|...:|.:|.:
 Frog   709 QKLLMPALQKLMATAVAHVANCELCQAKGFICEFCHGSDVIFPFQTEMCRRCEVCKTCYHKKCFS 773

  Fly   688 EKQPCPKCERIRKRE 702
            .:. ||||.||.:|:
 Frog   774 TRD-CPKCHRIERRK 787

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Plekhm1	NP_611639.1	RUN_PLEKHM1	20..191	CDD:439041	22/114 (19%)
		zf-RING_9	500..700	CDD:464030	66/201 (33%)
rubcnl	NP_001190195.1	zf-RING_9	586..785	CDD:464030	66/202 (33%)