DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment KCND3 and RpL37-1

DIOPT Version :10

Sequence 1:NP_004971.2 Gene:KCND3 / 3752 HGNCID:6239 Length:655 Species:Homo sapiens
Sequence 2:NP_573005.1 Gene:RpL37-1 / 32446 FlyBaseID:FBgn0030616 Length:93 Species:Drosophila melanogaster


Alignment Length:32 Identity:11/32 - (34%)
Similarity:15/32 - (46%) Gaps:5/32 - (15%)


- Green bases have known domain annotations that are detailed below.


Human   543 TTTCCSRRSKKTTHLPNS-----NLPATRLRS 569
            |.|.|.|..:.:.|:..|     ..||.:|||
  Fly    15 THTLCRRCGRSSYHIQKSTCAQCGYPAAKLRS 46

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
KCND3NP_004971.2 BTB_POZ_KCND3 6..143 CDD:349726
Interaction with KCNIP1 and KCNIP2. /evidence=ECO:0000269|PubMed:17187064, ECO:0000269|PubMed:34997220 6..21
Interaction with KCNIP1. /evidence=ECO:0000269|PubMed:17187064 70..78
Ion_trans 186..412 CDD:459842
Selectivity filter. /evidence=ECO:0000250|UniProtKB:P63142 367..372
DUF3399 468..563 CDD:463381 6/24 (25%)
Interaction with KCNIP1 and KCNIP2. /evidence=ECO:0000269|PubMed:34997220 470..487
Mediates dendritic targeting. /evidence=ECO:0000250|UniProtKB:Q63881 472..487
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 525..565 7/26 (27%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 615..655
RpL37-1NP_573005.1 PTZ00073 1..91 CDD:240257 11/32 (34%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.