DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13502 and Odad4

DIOPT Version :9

Sequence 1:	NP_611637.1	Gene:	CG13502 / 37518	FlyBaseID:	FBgn0034692	Length:	410	Species:	Drosophila melanogaster
Sequence 2:	NP_083194.2	Gene:	Odad4 / 74407	MGIID:	1921657	Length:	624	Species:	Mus musculus

Alignment Length:	236	Identity:	93/236 - (39%)
Similarity:	134/236 - (56%)	Gaps:	14/236 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   180 AIHFFCKALELNSTDINALISRSKCYLLLGEASKALQDAETALGEDKNNIRAIYQKAESLYYLGQ 244
            ||..|..||.|.|.|.|.|::||||||.:|:..|:|.|||.:|..|....:.|.||||:||.:|.
Mouse    30 AIQSFTNALHLQSGDKNCLVARSKCYLKMGDLEKSLNDAEASLRNDPTFCKGILQKAETLYTMGD 94

  Fly   245 FEQSLMFFHRGLRARPELALFRLGVQKTQEAIENTIGS----KPGPPGPTASVPKSGKSRKSGE- 304
            ||.:|:|:|||.:.||:.. |::|:||.||||.|::||    |....|..:.:.|..:|:|:.:
Mouse    95 FEFALVFYHRGYKLRPDRE-FKVGIQKAQEAINNSVGSPSSIKLENKGDLSFLSKQAESKKAQQK 158

  Fly   305 DTPKSQAAGATGTSARTRQKPSRADLERRNARKLLGELCVDKEYLEKLLLHPDLVRADTHTE-SI 368
            ..|..|.  :..|....::|.|..  ..:..|:|||||.|||||||||||..||::....:. ::
Mouse   159 HLPIKQL--SYSTKHEIKRKGSLK--SEKTVRQLLGELYVDKEYLEKLLLDEDLIKGTIKSGLTV 219

  Fly   369 SAYAREAVEFLNKRQEFWRQQRPCTALPNHKNLPHDALPKW 409
            .......:.:|:.|..|||||:|..|....:.|..:   ||
Mouse   220 EDLIMTGINYLDTRSNFWRQQKPIYARERDRKLMQE---KW 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13502	NP_611637.1	TPR repeat	165..189	CDD:276809	4/8 (50%)
		ANAPC3	174..252	CDD:289650	35/71 (49%)
		TPR repeat	194..224	CDD:276809	16/29 (55%)
		TPR repeat	229..257	CDD:276809	15/27 (56%)
Odad4	NP_083194.2	TPR 1. /evidence=ECO:0000255	11..44		7/13 (54%)
		TPR_11	14..76	CDD:290150	23/45 (51%)
		TPR repeat	14..39	CDD:276809	4/8 (50%)
		TPR repeat	44..74	CDD:276809	16/29 (55%)
		TPR 2. /evidence=ECO:0000255	46..78		16/31 (52%)
		TPR_11	47..110	CDD:290150	30/62 (48%)
		TPR 3. /evidence=ECO:0000255	79..112		17/32 (53%)
		TPR repeat	79..107	CDD:276809	15/27 (56%)
		TPR 4. /evidence=ECO:0000255	273..309
		TPR repeat	309..347	CDD:276809
		TPR_12	314..383	CDD:290160
		TPR 5. /evidence=ECO:0000255	318..351
		TPR 6. /evidence=ECO:0000255	358..391
		TPR repeat	358..383	CDD:276809
		TPR_12	359..427	CDD:290160
		TPR 7. /evidence=ECO:0000255	395..428
		TPR_12	396..466	CDD:290160
		TPR repeat	429..463	CDD:276809
		TPR 8. /evidence=ECO:0000255	435..468
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	511..624
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842306
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H12860
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0008154
OrthoInspector	1	1.000	-	-		oto95039
orthoMCL	1	0.900	-	-		OOG6_106567
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5221
SonicParanoid	1	1.000	-	-		X6115
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.770