DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Synj and INP54

DIOPT Version :9

Sequence 1:	NP_001246454.1	Gene:	Synj / 37517	FlyBaseID:	FBgn0034691	Length:	1218	Species:	Drosophila melanogaster
Sequence 2:	NP_014576.1	Gene:	INP54 / 854089	SGDID:	S000005426	Length:	384	Species:	Saccharomyces cerevisiae

Alignment Length:	361	Identity:	93/361 - (25%)
Similarity:	142/361 - (39%)	Gaps:	93/361 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   539 RVAVGTYNVNGGKHFRSIVFKDSLADWLLDCHALARSKALVDVNNPSENVDHPV----------D 593
            :|:|.|:|.  ||.|                 .:..|||:|      :.:..|.          |
Yeast     7 KVSVTTFNC--GKEF-----------------PVENSKAIV------KQLLFPYDDGISQLELQD 46

  Fly   594 IYAIGFEEIVDLNASNIMAASTD-------------NAKLWAEELQKTISRDNDYVLLTYQQLVG 645
            :|.:||:|:|.:...:..|.:.|             |.|:.|.:      .|..|..|....| |
Yeast    47 LYVLGFQEVVPIWQGSFPAVNRDLIDRITTTAVNCLNEKVSATQ------GDEQYSCLGVNSL-G 104

  Fly   646 VCLYIYIRPEHAPHIRDVAIDCVK-TGLGGATGN--KGACAIRFVL------HGTSMCFVCAHFA 701
            ....|.:...:|..::|   |.:| .|..|..|.  ||...|.|.:      :.....::|||..
Yeast   105 AITIIVLYNNNALKVKD---DILKRNGKCGWFGTHLKGGTLISFQMTRNGEENWERFSYICAHLN 166

  Fly   702 AGQSQVAERNADYAEITRKLAFPMGRTLKSHDWVFWCGDFNYRIDMEKD---------ELKECVR 757
            |.:. |..||....:..|.::......:...|..|:.||.|:|:....|         .|:..:.
Yeast   167 ANEG-VNNRNQRIDDYKRIMSEVCDSEVAKSDHFFFLGDLNFRVTSTYDPTTNYSSTTTLRRLLE 230

  Fly   758 NGDLSTVLEFDQLRKEQEAGNVFGEFLEGEITFDPTYKYDLFSDDYDTSEKQRAPAWTDRVLWRR 822
            |.:     |.:.|||.::.....| |.|.:|||.||||:.||  :.:|...:|.|:|.||:|:
Yeast   231 NHE-----ELNLLRKGEDEPLCKG-FQELKITFPPTYKFKLF--EKETYNTKRIPSWCDRILY-- 285

  Fly   823 RKALAEGDFAASAWNPGKLIHYGRSE-LKQSDHRPV 857
             |:.|...||    ..|......||. |..|||:||
Yeast   286 -KSYAVPTFA----QEGTYHSVPRSNALLFSDHQPV 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Synj	NP_001246454.1	Syja_N	61..353	CDD:280532
		INPP5c_Synj	538..863	CDD:197323	93/361 (26%)
		DUF1866	862..1008	CDD:286093
INP54	NP_014576.1	COG5411	1..371	CDD:227698	93/361 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5411
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810