DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Synj and BST1

DIOPT Version :9

Sequence 1:	NP_001246454.1	Gene:	Synj / 37517	FlyBaseID:	FBgn0034691	Length:	1218	Species:	Drosophila melanogaster
Sequence 2:	NP_001318880.1	Gene:	BST1 / 836633	AraportID:	AT5G65090	Length:	529	Species:	Arabidopsis thaliana

Alignment Length:	510	Identity:	140/510 - (27%)
Similarity:	200/510 - (39%)	Gaps:	191/510 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   517 APTTVLRELCKRYTEYVRPRMARVAVGTYNVNGGKHFRSIVFKDSLADWLLDCHALARSKALVDV 581
            ||||.:|||             ||.:.|:||.|......:    :|.|:||
plant    65 APTTEIREL-------------RVFLATWNVGGRTPNNDL----NLEDFLL-------------- 98

  Fly   582 NNPSENVDHPVDIYAIGFEEIVDLNASNIMAASTDN--AKLW----------------------- 621
                  |:...|:|..||:|||.|:|.|::... ||  |..|
plant    99 ------VEGTADLYICGFQEIVPLSAGNVLVVE-DNEPAAKWLALISQALNKPKQESVYSNAAYS 156

  Fly   622 -------------AEELQ-------------KTISRD---------------------------- 632
                         :||.:             |.:||:
plant   157 ASRTTTCSSSSCGSEESRAPSSLSFFQRPNLKVLSRNYRVDSSLLKTCNCPVIDTSVGWEARRSK 221

  Fly   633 --------------------------------------NDYVLLTYQQLVGVCLYIYIRPEHAPH 659
                                                  ..|.|:..:|:||:.|.::.|.|..||
plant   222 RFSDPSTDSSNNVEPENFRVHENFLFDDVPATTKMPGQMSYRLIASKQMVGLFLSVWARRELIPH 286

  Fly   660 IRDVAIDCVKTGLGGATGNKGACAIRFVLHGTSMCFVCAHFAAGQSQVAE--RNADYAEITRKLA 722
            |..:.:|.|..|:.|..||||..||...||.||.||||:|.|:|:.:..|  ||||.|||.:...
plant   287 ISHLRLDSVGRGIMGRLGNKGCIAISMSLHQTSFCFVCSHLASGEKEGDELRRNADVAEILKHTQ 351

  Fly   723 FP---------MGRTLKSHDWVFWCGDFNYRIDMEKDELKECVRNGDLSTVLEFDQLRKEQEAGN 778
            ||         ....:..||.|.|.||.|||:.:..:|.:..:.:.|..|:||.|||..|:.||.
plant   352 FPKLTKNPNCHAPERIIDHDRVLWLGDLNYRVALTYEETRVLLEDNDWDTLLERDQLNMERGAGR 416

  Fly   779 VFGEFLEGEITFDPTYKYDLFSDDY-----DTSEKQRAPAWTDRVLWRRRKALAEGDFAASAWNP 838
            ||..|.||:|.|.|||||...||.|     .:.:|:|.|||.||:||:     .||.
plant   417 VFSGFQEGQIFFAPTYKYSQNSDAYAGEMTKSKKKRRTPAWCDRILWK-----GEGI-------- 468

  Fly   839 GKLIHYGRSELKQSDHRPVIAI--IDAEIMEIDQQRRRAVFE----QVIRDLGPP 887
             :.:.|.|.|.:.||||||.||  ::.::..:::.|.|..:.    :::.|:..|
plant   469 -EQLSYIRGESRFSDHRPVCAIFAVEVDVKSLNKGRFRKGYSCAAVRLVEDVAIP 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Synj	NP_001246454.1	Syja_N	61..353	CDD:280532
		INPP5c_Synj	538..863	CDD:197323	129/459 (28%)
		DUF1866	862..1008	CDD:286093	4/30 (13%)
BST1	NP_001318880.1	EEP	71..496	CDD:382041	132/476 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	198	1.000	Domainoid score	I884
eggNOG	1	0.900	-	-		E1_COG5411
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.770