DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Synj and AT3G63240

DIOPT Version :9

Sequence 1:	NP_001246454.1	Gene:	Synj / 37517	FlyBaseID:	FBgn0034691	Length:	1218	Species:	Drosophila melanogaster
Sequence 2:	NP_001326750.1	Gene:	AT3G63240 / 825499	AraportID:	AT3G63240	Length:	547	Species:	Arabidopsis thaliana

Alignment Length:	566	Identity:	146/566 - (25%)
Similarity:	210/566 - (37%)	Gaps:	218/566 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly   442 WINNGNEVSKIYA-----GTGAIQGGSKLMDGARSAARTIQNNLLDNSKQEAIDVLLVGS-TLSS 500
            |:|..::....:|     |.|   ||.            .:||:::  ::||..|....: |.|.
plant    21 WLNIKSKSEDFHADDLDRGEG---GGD------------WRNNVIE--REEACSVRKSKTETRSK 68

  Fly   501 ELADRARILLPSNMLHAPTTVLRELCKRYTEYVRPRM--ARVAVGTYNVNGGKHFRSIVFKDSLA 563
            ..:.|||    .|.|.                |.|.:  .||...|:|| .||...|.:   :|.
plant    69 RNSGRAR----RNKLD----------------VDPPLDHLRVFTATWNV-AGKSPPSYL---NLD 109

  Fly   564 DWLLDCHALARSKALVDVNNPSENVDHPVDIYAIGFEEIVDLNASNIMAASTDN--AKLWAEELQ 626
            |||                    :...|.|||.:||:|||.|||.|:: .:.||  |:.|...::
plant   110 DWL--------------------HTSPPSDIYVLGFQEIVPLNAGNVL-GTEDNGPARKWVSLIR 153

  Fly   627 KTISR-------------------DND-------------------------------------- 634
            :|::.                   |:|
plant   154 RTLNSLPGGSCQTPSPVPHPVAELDSDFEGDSAAGANSLFYHRSRSMRMDASASSLPQQFDRRFS 218

  Fly   635 -----------------------------------------------------------YVLLTY 640
                                                                       |.|:..
plant   219 VCDRFMLGDTPDDFYDQSFRYCSSEDEPADSPCHDHYSPVSRTGSFVADDRDKGRDKSKYCLVAS 283

  Fly   641 QQLVGVCLYIYIRPEHAPHIRDVAIDCVKTGLGGATGNKGACAIRFVLHGTSMCFVCAHFAAGQS 705
            :|:||:.|.::::.:....:.::.:.||..||.|..||||:.:|...:|.||.||||:|..:||.
plant   284 KQMVGIFLTVWVKSDLRDSVNNLKVSCVGRGLMGYLGNKGSISISMSVHQTSFCFVCSHLTSGQK 348

  Fly   706 QVAE--RNADYAEITRKLAFP---------MGRTLKSHDWVFWCGDFNYRIDMEKDELKECVRNG 759
            :..|  ||:|..||.||..||         ..:.:..||.|.|.||.||||.:.....|..|...
plant   349 EGDELRRNSDVLEILRKTRFPRVNNAGDDKSPQMISEHDRVIWLGDLNYRIALSYRSAKALVEMR 413

  Fly   760 DLSTVLEFDQLRKEQEAGNVFGEFLEGEITFDPTYKY----DLFS-DDYDTSEKQRAPAWTDRVL 819
            |...:||.||||.||..|.||..:.||.|.|.|||||    |::: ||.....|:|.|||.||:|
plant   414 DWRALLEKDQLRIEQRKGCVFEGWKEGTIYFPPTYKYSNNSDIYAGDDRLPKAKRRTPAWCDRIL 478

  Fly   820 WRRRKALAEGDFAASAWNPGKLIHYGRSELKQSDHRPVIAIIDAEI 865
            |       .|...:.       :.|.|.|.:.||||||.::...||
plant   479 W-------HGSGISQ-------LSYVRGESRFSDHRPVYSLFSVEI 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Synj	NP_001246454.1	Syja_N	61..353	CDD:280532
		INPP5c_Synj	538..863	CDD:197323	123/458 (27%)
		DUF1866	862..1008	CDD:286093	2/4 (50%)
AT3G63240	NP_001326750.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	198	1.000	Domainoid score	I884
eggNOG	1	0.900	-	-		E1_COG5411
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	5	4.770