DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Synj and RHD4

DIOPT Version :9

Sequence 1:	NP_001246454.1	Gene:	Synj / 37517	FlyBaseID:	FBgn0034691	Length:	1218	Species:	Drosophila melanogaster
Sequence 2:	NP_190714.2	Gene:	RHD4 / 824309	AraportID:	AT3G51460	Length:	597	Species:	Arabidopsis thaliana

Alignment Length:	514	Identity:	159/514 - (30%)
Similarity:	257/514 - (50%)	Gaps:	67/514 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 PHSVLLEHRNKSDSILFE----SHAVALLTQ-QETDVIRKQYTKVCDAYGCLGALQLNAGESTVL 77
            |...::|..:.|.|...:    ..::.|:.| .|::.:|  ..|:...:|.:|.|:|.||.
plant    20 PDQYIIEPADGSGSSCLDISRVDASMKLIDQVPESNSVR--VPKIRSIFGVVGMLKLLAGS---- 78

  Fly    78 FLVLVTGCVSMGKIGDIEIFRITQTTFV----SLQNAAPNEDKI-SEVRKLLN-----SGTFYFA 132
            :||:||....:|......||::|....:    ||:|:...:.|: :|..|||:     :|.::
plant    79 YLVVVTESERVGSFLGHPIFKVTTLKVLPCDHSLKNSPEEQKKMETEFSKLLSVAEKTTGLYF-- 141

  Fly   133 HTNASASASGASSYRFDITLCAQRRQQT----------QETDNRFFWNRMMHIHLMRFGIDCQSW 187
                        ||..::||.:||..:.          ::.:.||.||..|...|:...:|  .:
plant   142 ------------SYEVNLTLSSQRLHEMGDESKSLPLWRQAEPRFLWNNYMLEVLIDNKLD--QF 192

  Fly   188 LLQAMCGSVEVRTVYIGAKQARAAIISRLSCERAGTRFNVRGTNDEGYVANFVETEQVIYVDGDV 252
            ||..:.||.......||.......:|:|....|.|||...||.:.:|||||||||||::.::|..
plant   193 LLPVIQGSFNSFETAIGRDIVDITLIARRCTRRNGTRMWRRGADLDGYVANFVETEQIVQMNGYT 257

  Fly   253 TSYVQTRGSVPLFWEQPGVQVGSHKVKLSRGFETSAAAFDRHMSMMRQRYGYQTVVNLLGSSLVG 317
            :|:||.|||:|..|||........|.::.:..|....| :||...:|::||     ::|...||.
plant   258 SSFVQVRGSMPFMWEQVVDLTYKPKFEIVQPEEAKRIA-ERHFLDLRKKYG-----SVLAVDLVN 316

  Fly   318 SKEGEAMLSNEFQRHHGMSAHKDVPHVVFDYHQECRGGNFSALAKLKERIVACGANYGVFHAS-N 381
            .:.||..|..::..........|:.::.||:||.|...:|..|:.|.|:|.......|.|..: .
plant   317 KQGGEGRLCEKYATVMQHITGDDIRYLHFDFHQICGHIHFERLSILYEQIEGFLEKNGYFLLNEK 381

  Fly   382 GQVLREQFGVVRTNCLDCLDRTNCVQTYLGLDTLGIQLEALKMGGKQQNIS---RFEEIFRQMWI 443
            |:.::||.||||:||:|||||||..|:.:|...|.:||:.:.:.|.::.||   .|:|.::.:|.
plant   382 GEKMKEQLGVVRSNCIDCLDRTNVTQSMIGRKMLEVQLKRIGVFGAEETISSHLNFDEHYKILWA 446

  Fly   444 NNGNEVSKIYAGTGAIQG-----GSK-----LMDGARSAARTIQNNLLDNSKQEAIDVL 492
            |:|:|:|..|:||.|::|     |.:     |.||..|..|...||..|.:||:|||:|
plant   447 NHGDEISIQYSGTPALKGDFVRYGHRTAHGVLKDGWSSLRRYYLNNFADGTKQDAIDLL 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Synj	NP_001246454.1	Syja_N	61..353	CDD:280532	91/311 (29%)
		INPP5c_Synj	538..863	CDD:197323
		DUF1866	862..1008	CDD:286093
RHD4	NP_190714.2	COG5329	65..551	CDD:227637	150/467 (32%)
RHD4	NP_190714.2	Syja_N	66..351	CDD:280532	91/310 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D359616at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920